University of Athens, Greece
Research Interest: Natural Product Chemistry,
Medicinal Chemistry, Chemical Biolgoy
Research Interest: "Targeted drug delivery; Chemical functionalization of nanoparticles; Chemical composition-biological behavior relationship of nanoparticles; Biomaterials for immunotherapy; Nanomedicine; Pharmaceutical Nanotechnology; Nanovaccines; Immunotoxicity of nanoparticles; Surface biofunctionalization of the nanoparticles with antibodies and peptides; Cell-nanoparticle interactions
Research Interest: Asymmetric synthesis, total
synthesis of natural products, multi-component reactions, heterocyclic
synthesis and green chemistry
Research Interest: Isolation and structural elucidation of biologically active metabolites from natural sources (Plants, Bacteria, Marine and Fungi). Phytochemical characterization of plant extracts used in traditional medicine, their pharmacological evaluation, and the isolation and identification of their active constituents
Research Interest: Phenolic content and antioxydant
activity of medicinal plants, Anti-inflammatory, analgesic and antipyretic
activities of medicinal plants, Mutagenic and anticancer effects of medicinal plants.
NF-κB pathway inhibition, Antileishmanial and antitrypanosomal activities of
medicinal plants, Antioxidant, anticancer, mutagenic, Anti-inflammatory,
Analgesic, Antipyretic, Antiparasitic, Polyphenols, Flavonoïds, medicinal
Research Interest: Medicinal Chemistry.
Research Interest: Topics in chemical quality
control in pharmacy practice; Application of different analytical techniques
for the determination of pharmaceuticals in the presence of their degradation
product(s) including; Different spectrophotometric methods such as colorimetry,
derivative and derivative-ratio spectrophotometry. Different chromatographic methods
such as TLC-densitometry, Preparative TLC, Two-dimensional TLC, GC and HPLC. Monitoring
of the degradation profile of the pharmaceuticals and kinetic studies. Synthesis
of the degradation product(s) of the selected drugs and structure elucidation.Chemometric
methods, such as CLS, PCR and PLS.
Research Interest: Isolation and structural
elucidation of biologically active metabolites from natural sources (Plants and
Fungi); Marine natural products chemistry and biology; Phytochemical
characterization of plant extracts used in traditional medicine, their
pharmacological evaluation, and the isolation and identification of their
Research Interest: Organic chemistry, molecular imaging and bioorganic chemistry, including organofluorine chemistry, asymmetric synthesis and catalysis, and the relevant mechanistic studies using various physical organic chemistry tools, molecular imaging, PET/Fluorescence/MRI multi modality imaging, inhibited tumor growth suppresion, and nanoparticle assembled drug delivery
Christoforos G. Kokotos is an Assistant Professor of Organic Chemistry at the Department of Chemistry, National and Kapodistrian University of Athens, Greece, with undergraduate studies at the University of Athens, PhD studies at the University of Bristol, UK (Prof. Varinder Aggarwal) and post-doctoral studies at Princeton University, USA (Prof. David W. C. MacMillan). His research interests focus on the development of novel asymmetric organocatalytic methodologies, green and sustainable organocatalytic oxidations, Photocatalysis, their application in the synthesis of pharmaceuticals, compounds of biological importance and natural products and the study of the mechanisms of organic transformations employing modern techniques, like HRMS. He is co-author of 71 peer-reviewed papers, 4 book chapters, 2 patents, >40 presentations in conferences. He is the recipient of prestigious awards, like the Hildergard-Zervas Award, Academy of Athens (2016 and 2018), JSP fellowship for the Burgenstock Conference (2016), Young Investigators Workshop (3 times representing Greece, 2014, 2017 and 2018) and ACS Young Academic Investigators Award (2014, representing Europe).
Research Interest: Organic Chemistry, Food Chemistry, Green Chemistry
Grants: (1) Research Funding Scheme Post-doc, “PEPCAT-Novel Organocatalysts Based on Peptides and Amino Acids and their Application in Asymmetric Organic Transformations”, General Secretariat for Research and Development (2012-2015, 150.000 €).
(2) Organocatalysis – ORCA, Cost Action CM0905 funded by the intergovernmental framework for European Cooperation in Science and technology (2011-2014), Management Committee Substitute and co-Organizer of the third ORCA meeting in Athens, 2012. Action Chair: Prof. P. Pihko, University of Jyvskyl, Finland.
(3) Research Proposal Funding Scheme, John Latsis Foundation “PhotoOrganocatalysis: Development of new environmentally-friendly methods for the synthesis of compounds for the pharmaceutical and chemical industry” (2015, 12.000€).
(4) C-H Activation in Organic Synthesis – CHAOS, Cost Action CM15106 funded by the intergovernmental framework for European Cooperation in Science and technology (2016-2020), Management Committee Substitute. Action Chair: Prof. M. Schnurch, Technical University of Vienna, Austria.
(5) Fellowship for PhD programme, Ms Errika Voutyritsa, State Scholarships Foundation (IKY), 2016.
(6) Fellowship for PhD programme, Ms Ierasia Triandafillidi, Hellenic Foundation for Research and Innovation (ELIDEK), 2017.
(7) Fellowship for PhD programme, Mr Nikolaos Nikitas, State Scholarships Foundation, 2018.
(8) European Network on Pseudomyxoma Peritonei – PMP, Cost Action CA17101 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Kjersti Flatmark, Oslo University Hospital, Norway.
(9) Chemobrionics, Cost Action CA17120 funded by the intergovernmental framework for European Cooperation in Science and technology (2019-2023), Management Committee Member. Action Chair: Prof. Julyan Cartwright, CSIC Granada, Spain.
(10) Fellowship for PhD programme, Ms Nikoleta Spiliopoulou, Hellenic Foundation for Research and Innovation (ELIDEK), 2019.
(11) Research Funding Scheme Teams of Young Investigators, “Green and Sustainable Organocatalysis: Novel Epoxidation reactions and their application in Chemical Industry”, General Secretariat for Research and Development (2019-2021, 50.000 €).