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    Dissolution testing of prolonged-release tablets using experimental design approach

    DOI Logo 10.17352/ojabc.000022

    Published On: October 06, 2020 | Pages: 034 - 039

    Author(s): Blagica Manchevska*, Filip Smilcevski, Maja H Gigovska, Packa Antovska and Sonja Ugarkovic
    Dissolution testing is an essential tool in the pharmaceutical industry and is used in formulation and process development, in monitoring of the manufacturing process, as a quality control test, to predict the in vivo performance. The purpose of this study is to evaluate the behaviour of the test and reference products using conventional dissolution apparatus basket a ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    mendeley

    Designing and evaluating analytical parameters to adapt siemens urinary creatinine enzymatic method to open system analysers

    DOI Logo 10.17352/ojabc.000021

    Published On: September 17, 2020 | Pages: 029 - 033

    Author(s): Ashraf Mina*, Leah McNeice, Shanmugam Banukumar and Santiago Vazquez
    Urinary creatinine is measured to assess kidney function and also as part of sample validity testing in drugs of abuse. Creatinine methods based on alkaline picrate Jaffé’s reaction require extra cleaning on chemistry analysers to minimise any interference from picric acid and sodium hydroxide on other reagents on board. Enzymatic methods reagents are not as invasive ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    mendeley

    Triosephosphate isomerase from baker’s yeast – ribozyme versus protein

    DOI Logo 10.17352/ojabc.000020

    Published On: August 18, 2020 | Pages: 020 - 028

    Author(s): ON Solovjeva*
    It was previously shown that in baker’s yeast Saccharomyces cerevisiae, transketolase can exist not only free, but in complex with RNA. The complex does not possess transketolase activity [N.K. Tikhomirova, G.A. Kochetov, A new method of isolation and a new form of transketolase from baker’s yeast, Biokhimiia 56 (1991) 1123-1130]. We discovered that this RNA is a ri ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    mendeley

    Application of Pollution Load Indices, Enrichment Factors, Contamination Factor and Health Risk Assessment of Heavy Metals Pollution of Soils of Welding Workshops at Old Panteka Market, Kaduna-Nigeria

    DOI Logo 10.17352/ojabc.000019

    Published On: August 07, 2020 | Pages: 011 - 019

    Author(s): Abdullateef Jimoh*, Edith B Agbaji, Victor O Ajibola and Mustapha A Funtua
    The concentration of five soil heavy metals ions (Cr6+, Cu2+, Cd2+, Pb2+, and Ni2+) was measured in eleven sampling sites along Old Panteka market Kaduna from two different depths. These chemical elements in the samples were determined using atomic absorption spectrometer. The assessment of heavy metal pollution was derived using the Enrichment Factors (EF) and geoacc ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    mendeley

    A fluorescence enhancement assay for measurement of glutamate decarboxylase activity

    DOI Logo 10.17352/ojabc.000018

    Published On: June 29, 2020 | Pages: 007 - 010

    Author(s): Manoochehr Messripour* and Azadeh Mesripour
    Glutamic Acid Decarboxylase (GAD) is an enzyme that converts glutamate to γ-aminobutyric acid (GABA) both in the brain and pancreatic β-cells. Several analytical methods are described for quantitative assay of GAD, where little attention has been given to the enzyme regulation in tissues, in part, due to the complexity of the methods. In this study, a novel fluorimetr ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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