Research Interest: Gene therapy, Cell and tissue
engineering, Vaccine development, Biomaterials, Synthetic biology and biomass,
Research Interest: Epigenetic regulation of virus or
autoimmune diseases on host immune cells such as Treg, Th17 and innate lymphoid
Research Interest: Allergy, Allergens, Carbohydrates, cross-reactive
Immunomodulation, Antibody engineering, Molecule design, Molecular biology and biochemistry
Research Interest: They relate to functions within
Ministry of research (head of mission of the Life Sciences), CNRS (medical
advisor for the life sciences), INSERM, ANRS, advisor for clinical Research,
and for International Affairs APHP/public hospitals of Paris.
Research Interest: My Research Focus on Design Universal and
Live Attenuated Influenza Vaccine by using Novel Methods, and Testingthese New
Generation Vaccine Candidates in Humanized Mice and Ferrets. As Well, We would like
to explore the Mechanism of Cross-Protection induced by live Attenuated
Influenza against seasonal and Pandemic Influenza Viruses. Our Results
Suggested That Activation of T cell Is Crucial for the cross Protection
Stimulated By vaccination With Live Attenuated Influenza Vaccine. In Future
Research, We Will Focus on B Cell Development Stimulated by Vaccination with
Live Attenuated Influenza vaccine. To Facilitate The Development Of More
Effective Vaccines, We Are Also Researching: The Effect Of Current Vaccination
Programs On The Epidemiological Changes Of Respiratory Pathogens (Strain
Replacement And Antigenic Variation); How People Respond To Infections Or
Vaccinations At The Cellular And Molecular Levels (B Cell, T Cell, And Gene expression
Levels) identification of New Protective Antigens Through Genomic And Proteomic
Research Interest: Antigen processing and presentation,
relating to the understanding of these processes and manipulation of them in
order to treat.
Research Interest: Bacteria of the genus Staphylococcus,
in particular the species S. aureus and virulence factors produced by this
species. In the so far carried out research, the results of which were
published in several peer-reviewed journals I analyzed:
1.The influence of
leucocytotoxic and superantygenic virulence factors produced by S. aureus
strains isolated from milk of cows with mastitis on the cytokine production and
gene expression in bovine leukocyte cultures in vitro;
2. the impact of staphylococcal exotoxins on the process of phagocytosis in vitro;
3. the efficacy of treatment of mastitis by staphylococcal autovaccine;
4. the profile of resistance to methicillin of coagulase-negative staphylococci isolated from animals;
5. the profile of the genes encoding superantigens in S. aureus and S. xylosus isolates collected from cows;
6. the possibility of transfer of genes encoding superantigens between staphylococci occurring in the same mammary gland;
7. genetic relatedness of staphylococci isolated within a herd of animals;
8. the biological activity of staphylococcal exosecretions against leukocytes in vitro;
9. the impact of staphylococcal virulence factors on the morphology of leukocytes in vitro.
I also analyzed and published in the GenBank several new 16S rRNA gene sequences of bacteria representing different species of staphylococci, identified by PCR-RFLP analysis of gap gene. Furthermore, as a contributor I published in the GenBank the 16S rRNA gene sequences of bacterial isolates, which were unidentified based on the polymorphism of gap gene, of which at least two isolates represent new species or subspecies of the staphylococci.
The second direction of my research concerns the use of magnetic fields, in particular the rotating magnetic field to modify the functional parameters and pathogenicity potential of different species of microorganisms. At the present, I’m analyzing the influence of magnetic field on metabolic processes in microorganisms, both at the cellular and molecular level. As a continuation of my first research mainstream microorganism used in these studies is primarily S. aureus.
Research Interest: Inflammatory bowel diseases coeliac
disease, Cystic fibrosis.
Research Interest: Immune based inflammatory disorders
(with special reference to nanomedicines).
Research Interest: Structural determination of
protein-DNA, Solid: X-ray, Solution: 2D & 3D NMR, and Gas: Mass
Spectrometry, interactions and their pathways, stability, dynamics, and
Research Interest: Immunology, veterinary immunology,
lymphocytes, innate immunity, receptors, viral infections, RNA viruses.
Research Interest: Nanoparticles, liposomes,
solid lipid naonparticles, and anhydrous reverse micelles, drug/vaccine
carriers, freeze-drying of pharmaceutics, design, carrying out and analysis of
in vivo tests, separation and purification of chemicals, extraction and
analysis of therapeutic.
Research Interest: Virology/Microbiology, Biochemistry, Clinical Diagnostics, Molecular
Biology, Protein Chemistry.
Research Interest: A specialist in pediatrics and
Research Interest: Endocrine and metabolic diseases in
prostate cancer, bone metabolism, renal function, and immune structure in
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