Research Interest: Molecular Imaging, Contrast Agent Development,
Radiochemistry, In Vitro And In Vivo Models Of Cancer, And
Pharmacological Evaluation Of Novel Compounds
Research Interest: Analytical chemistry related to pharmaceutical
Research sector in developing analytical methods and validations
through Research and development in line with the organizational
objectives
Research Interest: "Developed
generic pharmaceutical dosage forms based on industrial QbD approach �
Involved in designing, conducting and supervising formulation
development, process development, process optimization, scale up and
manufacturing process � Identified quality target product profile,
critical quality attribute, created design space by DOE, perform risk
assessment and initiate control strategies � Performed pre-formulation
and formulation studies (solubility, dissolution rate, permeation,
accelerated stability, compatibility, rheology) "
Research Interest: The role of 5 ectonucleotidase (CD73) and
ectoapyrase (CD39), Enzymes that convert extracellular ATP in
adenosine in inflammatory process and cardiovascular system.
Research Interest: Natural products in the treatment of neoplastic diseases, Biological mechanisms of natural products inducing
apoptosis, Autophagy and inhibiting invasion/migration of cancer cells, Studies focused also on the cytotoxicity activity and the
mechanism of natural compounds in oral cancer cells.
Dr. Mehmet Evren Okur has completed her Ph.D from Faculty of Pharmacy, Anadolu University. His PhD thesis was “Investigation of the hypoglycemic effects and mechanisms of Capparis ovata var. palaestina in mice.’’ He has original research articles on nanotechnology and drug delivery systems. He has 21 original research articles on pharmacology in various journals and several oral/poster presentations in international and national congresses. He interested to wound healing, diabetes mellitus, dermal drug delivery, nephrotoxicity animal models, skin irritation studies, eye diseases models.
List of Publications:
1. Okur M.E., Karantas I.D., Üstundağ-Okur N., Siafaka P.I., (2017). Hypertension in 2017: Update in treatment and pharmaceutical innovations, Current Pharmaceutical Design, 23(44): 6795-6814. DOI: 10.2174/1381612823666170927123454.
2. Okur M.E., Özbek H., Çiçek Polat D., Yılmaz S., Arslan R., (2018). Hypoglycemic activity of Capparis ovata desf. var. palaestina zoh. methanol exracts, Brazilian Journal of Pharmaceutical Sciences, 54(3). DOI: 10.1590/s2175-97902018000318031.
3. Okur M.E., Çiçek Polat D., Özbek H., Yılmaz S., Yoltaş A., Arslan R., (2018). Evaluation of the antidiabetic property of Capparis ovata desf. var. palaestina zoh. extracts using in vivo and in vitro approaches, Endocrine, Metabolic & Immune Disorders-Drug Targets, 18. DOI : 10.2174/1871530318666180328110524.
4. Okur M.E., Karantas I.D., Siafaka P.I., (2017). Diabetes Mellitus: A Review on Pathophysiology, Current Status of Oral Medications and Future Perspectives, Acta Pharmaceutica Sciencia, Vol 55 No: 1., 61- 82. DOI: 10.23893/1307-2080.APS.0555.
5. Üstündağ Okur N., Filippousi M., Okur, M.E., Ayla Ş., Çağlar E.Ş., Yoltaş, A., Siafaka P.I. (2018). A novel approach for skin fungal infections: Controlled release topical mats of poly(lactic acid)/poly(ethylene succinate) blends containing Voriconazole, Journal of Drug Delivery Science and Technology, Vol 46, (2018) 74–86. https://doi.org/10.1016/j.jddst.2018.05.005. 6. Okur M.E., Ayla Ş., Çiçek-Polat D., Günal M.Y., Yoltaş A., Biçeroğlu Ö., (2018). Novel insight into wound healing properties of methanol extract of Capparis ovata desf. var. palaestina zoh. fruits, Journal of Pharmacy and Pharmacology. (accepted) 7. Ayla Ş., Günal M.Y., Özdemir E.M., Okur M.E., Biçeroğlu Ö., Yoltaş A., Karahüseyinoğlu, S., Çiçek-Polat D. (2018). Evaluation of wound healing, antimicrobial and antioxidant potential of methanol extract of the Laurocerasus officinalis roem., Biotechnic and Histochemistry (accepted) 8. Siafaka P.I, Okur, M.E., Ayla Ş., Er, S., Çağlar, E.Ş., Üstündağ Okur N. (2018). Design and characterization of nanocarriers loaded with Levofloxacin for enhanced antimicrobial activity: Physicochemical properties, in vitro release and acute oral toxicity, Brazilian Journal of Pharmaceutical Sciences, (accepted) 9. Ayla Ş., Günal M.Y., Sayın-Şakul A.A., Biçeroğlu Ö., Özdemir E.M., Okur M.E., Çiçek-Polat D., Üstundağ-Okur N., Bilgiç B.E., (2017). Prunus spinosa L. meyvelerinin deneysel yara iyileşmesi üzerine etkileri, Medeniyet Medical Journal 32(3):152-158. DOI:10.5222/MMJ.2017.152 .
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