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    Tumor-associated macrophages: Shifting bad prognosis to improved efficacy in cancer therapies?

    DOI Logo 10.17352/2455-8591.000032

    Published On: May 15, 2021 | Pages: 015 - 023

    Author(s): Guillaume Harlé, Janske Nel, Camille Corbier, Nadège Touche and Stéphanie Grandemange*
    Macrophages are innate immune cells that play an important role in the response to damaged tissue and pathogenic infection. During activation, signals from the local environment induce macrophage polarization towards either the classical pro-inflammatory phenotype (M1) or towards the alternative anti-inflammatory phenotype (M2). In cancer, M2 tumor-associated macropha ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Rosuvastatin inhibit the cell proliferation and the expression of angiogenic factors Vascular Endothelial Growth Factor and Matrix-Metalloproteinase-9 in DU-145 human prostate cancer cells

    DOI Logo 10.17352/2455-8591.000031

    Published On: May 11, 2021 | Pages: 008 - 014

    Author(s): Abdolkhaleg Deezagi*, Armaghan Jamalnia and Hanieh Jaefary
    Abstract Background: Pathophysiology angiogenesis refers to uncontrollable endothelium capillary proliferation, it can be seen in diseases such as growth and metastasis of tumors. The aim of this was to study the effects of Rosuvastatin on the cell growth and expression of the Vascular Endothelial Growth Factor (VEGF) and matrix metal proteases (MMP-9) genes in human ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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    Understanding immunotherapy and its management

    DOI Logo 10.17352/2455-8591.000030

    Published On: January 12, 2021 | Pages: 001 - 007

    Author(s): Nadiminti Rajesh Kumar* and Sajid Alvi
    A few tumours are exceptionally stubborn to oral chemotherapy. The endurance of tumours in a few cases is helped by checkpoint immunomodulation to keep up the unevenness between resistant reconnaissance and disease cell division. Checkpoint counteracting agent inhibitors, for example, against PD-1/PD-L1, are another class of inhibitors that capacity has tumour stiflin ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
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