Research Interest: Immunology such as Autoimmune Diabetes (Type 1).

Research Interest: Blood Brain Barrier; Neurovascular Pharmacokinetics; Stroke; Ischemia; Neurodegneration; Neuroprotection; Neuropharmacology; Nutrient and Ion Transporters; Diabetes

Research Interest: It is Mainly Lies in Two Areas. First I Focused on Applying Statistical Methods and Multilevel Modeling in Randomized Clinical Trials and Family-Based Health-Related Interventions, Particularly in Substance Abuse, HIV/AIDS, STD, Sexual Risk Behaviors and Minority Health Disparities. Second, I am Interested in Epidemiology Studies 0f Chronic Disease Including Alcohol Use Disorder, Drug Abuse, Obesity, Diabetes, Metabolic Syndrome, Hypertension, Cardiovascular Disease and Stroke; and Also from Genetic Epidemiology Point of View to Examine Complex Disease Including Alcohol Dependence and Co-Morbidity, and Alzheimer Disease Etc. 

Research Interest: Her Clinical and Research Interest Focuses on Diabetes Management, Cardiovascular Risk, Flow Cytometry-Based Study of Endothelial Dysfunction, Novel Therapy for Type 2 Diabetes, Clinical Nutrition and Mediterranean Diet

Research Interest:

1. Obesity and metabolic diseases
2. Effect of sport in obesity and cardio-metabolic disturbances
3. Role of environmental pollutant in cardio-metabolic diseases

List of Publications:

1.    Della Guardia L, Shin AC. The role of adipose tissue dysfunction in PM2.5-induced vascular pathology. Am J Physiol Heart Circ Physiol. 2022 Jun 1;322(6):H971-H972. doi: 10.1152/ajpheart.00156.2022
2.    De Nardi M, Bisio A, Della Guardia L, Facheris C, Faelli E, La Torre A, Luzi L, Ruggeri P, Codella R. Partial-Body Cryostimulation Increases Resting Energy Expenditure in Lean and Obese Women. Int J Environ Res Public Health. 2021 Apr 14;18(8):4127. doi: 10.3390/ijerph18084127.
3.    Della Guardia L, Shin AC. White and brown adipose tissue functionality is impaired by fine particulate matter (PM2.5) exposure. J Mol Med (Berl). 2022 May;100(5):665-676. doi: 10.1007/s00109-022-02183-6. Epub 2022 Mar 14
4.    Della Guardia L, Codella R. Exercise tolls the bell for key mediators of low-grade inflammation in dysmetabolic conditions. Cytokine Growth Factor Rev. 2021 Dec;62:83-93. doi: 10.1016/j.cytogfr.2021.09.003.
5.    Codella R, Della Guardia L, Terruzzi I, Solini A, Folli F, Varoni EM, Carrassi A, Luzi L. Physical activity as a proxy to ameliorate inflammation in patients with type 2 diabetes and periodontal disease at high cardiovascular risk. Nutr Metab Cardiovasc Dis. 2021 Jul 22;31(8):2199-2209. doi: 10.1016/j.numecd.2021.04.022.
6.    Della Guardia L, Codella R. Airways to heaven: Caution needed when exercising during COVID-19. Med Hypotheses. 2021 Mar;148:110522. doi: 10.1016/j.mehy.2021.110522.
7.    Moreno C, Della Guardia L, Shnyder V et al. iPSC-derived familial Alzheimer's PSEN2 N141I cholinergic neurons exhibit mutation-dependent molecular pathology corrected by insulin signal. Mol Neurodegener. 2018 Jun 26;13(1):33. doi: 10.1186/s13024-018-0265-5.
8.    Maurizi G, Babini L, Della Gaurdia L. Potential role of microRNAs in the regulation of adipocytes liposecretion and adipose tissue physiology. Journal of Cellular Physiology.
9.    Della Guardia L, Thomas MA, Cena H. Insulin Sensitivity and Glucose Homeostasis Can Be Influenced by Metabolic Acid Load. Nutrients 2018, 10, 618; doi:10.3390/nu10050618
10.    Maurizi G, Petäistö T, Maurizi A, Della Guardia L. Key-genes regulating the liposecretion process of mature adipocytes. J Cell Physiol. 2018 May;233(5):3784-3793.
11.    Manuelli M, Della Guardia L, Cena H. Enriching Diet with n-3 PUFAs to Help Prevent Cardiovascular Diseases in Healthy Adults: Results from Clinical Trials. Int J Mol Sci. 2017 Jul 18;18(7)
12.    Maurizi G, Della Guardia L, Maurizi A, Poloni A. Adipocytes properties and crosstalk with immune system in obesity-related inflammation. J Cell Physiol. 2018;233:88–97.
13.    Della Guardia L, Roggi C, Cena H. Diet-induced acidosis and alkali supplementation. Int J Food Sci Nutr. 2016 Jun 24:1-8.
14.    Della Guardia L, Cavallaro M, Cena H. The risks of self-made diets: the case of an amateur bodybuilder. J Int Soc Sports Nutr. 2015 Apr 1;12:16.
15.    Della Guardia L. Guarene M. Calcaterra V Vandoni M Cena H. Effects of a multidisciplinary intervention on childhood obesity". 2nd N&G conference Barcelona. 30 Jen-2 Feb 2014.
16.    Guarene M. Calcaterra V, De Giuseppe R, Della Guardia L, et al. Lifestyle, nutritional Knowledge and fears of a group of adolescents suffering from type 1 diabetes. Clin Nutr 2014 Sep (Supp); 33:S174

Dr. Ahed J Alkhatib is currently working as a researcher in Department of Forensic Science and Toxicology, Jordan University of Sciences and Technology, Jordon from 2011 to till date. He completed his PhD in Campbell University, medical technology, North Carolina, USA from 2008 to 2011. Dr. Ahed J Alkhatib is a member of council of nutritional and environmental disease (CONEM). He is conducting research that generates new theories. Dr. Ahed J Alkhatib has done 116 Publications. He is establishing new science (molecular sociology).

Research Interest:  Neurology; Pharmacology; diabetes; Philosophy of science; Tumor research; Behavioral biology; Emergency medicine

List of Publications:

1-    Amro Saleem Falah Alamaren and Ahed J. Alkhatib (2019). The Relationship Between Financial Stability and Insurance. International Business Management, 13: 130-133.

2-    Ahed J Alkhatib (2019). Expression and Releasing of Cell Cycle Proteins by Candida albicans into Surrounding Tissue: New Perspectives of the Relationship between Microbes and Host. EC Microbiology, 15 (3): 168-171.

3-     Samirah Fahad A, Ahed Alkhatib (2019). The Assessment of Intervention Programs for Autism Including Children and their Parents. Am J Biomed Sci & Res., 1(6): 236-238. AJBSR.MS.ID.000553.

4-    Kawther Faisal Amawi, Inas Saleh Al-Mazari, Ali Alsarhan, Hamza Qasim Mohammad Alhamad, Ahed J. Alkhatib (2019). Diabetes upregulates the expression of HSP90 and downregulates HSP70 in the liver of diabetic rats. Comparative Clinical Pathology, 28 (2): 473-478.

5-    Ahed J. Alkhatib (2019). The Progression of a Disease Depends on Downregulation of Heat Shock Protein 70 (HSP70) And Upregulation of Inducible Nitric Oxide Synthase (iNOS): A New Medical Hypothesis. Biomed Discoveries: 1-3, DOI: 10.29011/ BMDC-103. 100003.

6-    Mohammad A. Bani-Ahmad, Suleimman A. Al-Sweedan, Mohammad A. Al-Asseiri, Ahed J. Alkhatib (2018). A Proposed Kinetic Model for the Diagnostic and Prognostic Value of WT1 and p53 in Acute Myeloid Leukemia. Clinical laboratory, 64 (3):357-363. doi: 10.7754/Clin.Lab.2017.170915.

7-    Ahed J Alkhatib, Ilham Ahed Alkhatib (2018). Metformin and Urtica pilulifera: Comparable Effects and Similar Actions in Diabetes. Int J Pharm,  8(3): 1-2.

8-    Ahed J Alkhatib (2018). White Matter Ageing: Etiology and Prognosis. Appl Cell Biol, 6 (2), 14-17.
 
9-    Khaled Z. Alawneh, Liqaa A. Raffee, Haytham A. Al Ewaidat and Ahed J. Alkhatib (2018).. The Impact of Exposure to Medical Radiation on Lead (Pb+2) and Thyroid Function Test. Research Journal of Medical Sciences, 12: 31-34.

10-    Hani A. Masaadeh, Ali Alrifai, Ahed J Alkhatib and Mamdoh Meqdam (2018). Molecular Epidemiology of Extended-Spectrum β-Lactamase-ProducingK. pneumoniae in Northern Jordan. Research Journal of Medical Sciences, 12: 63-69.

11-    Ahed J Alkhatib (2018). Does Epstein - Barr Virus Cross Talks with Sex Hormone Receptors on Lymphoid Cells Differently to Produce Lymphoma? Int J Pharm, 8(1): 56-57.

12-    Ahed J Alkhatib (2018). Non-classical Roles of Microbes.  PSM Microbiol., 3(2): 62-63.

13-    Sani S Bala, Ahed J Alkhatib, SS Bashir, Abdulhadi M (2018). Photocatalytic Degradation of Indigo Carmine in Aqueous Solutions by the Antibacterial Agent Pefloxacin and UVA. Biomed J Sci&Tech Res 5(5), DOI: 10.26717/ BJSTR.2018.05.001275.

14-    Sonia Cherian, Ahed J Alkhatib, Megha Aggarwal (2018). Relationship between organizational commitment and job satisfaction of nurses in Dubai hospital. Journal of Advances in Social Science and Humanities, 4(1): 36373-36400.

15-    Amro Saleem Falah Alamaren, Ahed J Alkhatib (2018). Financial Aspects Associated with Overuse of Health Resources. Biomed J Sci&Tech Res 7(1). BJSTR. MS.ID.001444. DOI: 10.26717/ BJSTR.2018.07.001444.

16-    Ahed J Alkhatib, Khalid Alzaailay (2018). The Appropriate Use of Activated Charcoal in Pharmaceutical and Toxicological Approaches. Biomed J Sci & Tech Res, 5 (2),

17-    Ahed J Alkatib (2017). Diabetes and diabetic neuropathies are independent events: a new medical hypothesis. Ind Res J Pharm & Sci, 4 (3): 1064-1067.


18-    Ahed J Alkhatib (2019). The Use of Crude Extract of Alhagi graecorum and Urtica pilulifera in the Treatment of Chronic Inflammation of Seminal Fluid: A Case Study. Open Acc J Comp & Alt Med 1(4): 62-64.

19-    Ahed J Alkhatib (2019). New Insights to Diabetes: Is Diabetes a Metabolic Disorder or a Neurological Disease? International Journal of Diabetes & Metabolic Disorders, 4 (1).

20-    Ahed J Alkhatib (2019). White Matter: Structural and Functional Roles in Health and Disease. PSM Biological Research, 4 (1): 17-19.

21-    Ahed J Alkhatib (2018). The role of natural antioxidants in declining memory defects in Alzheimer’s disease. J Spine Neurosurg, 7, DOI: 10.4172/2325-9701-C7-030.

22-    Alkhatib, A. J., (2018). Crude Extract of Potato Ameliorates Clinical Impacts of Infection with Helicobacter pylori: Case Study. PSM Microbiol. 3(2): 64-66.

23-    Ahed J Alkhatib (2018). It is time to change the concept of herbal use to molecular food. Ind Res J Pharm & Sci, 5 (4): 1648.

24-    Ahed J Alkhatib, Ilham Ahed Alkhatib, Kawther Faisal Amawi, Ali Alsarhan, Suha K Ababneh (2018). Sickle cell disease: molecular and pathophysiological features. Ind Res J Pharm & Sci, 5 (1), 1251-1259.

25-    Ahed J Alkhatib, Nayef Alzame (2018). Neurotoxicity and criminal behavior. Indian research journal of pharmacy and science, 5 (2): DOI: 1234-1238. 10.26717/BJSTR.2018.05.001170.

26-    Ahed J Alkhatib (2018). WHITE MATTER ASSOCIATED DISEASES.  Indian research journal of pharmacy and science, 5 (2): 1416-1419.

27-    Ahed J Alkhatib, Sani S. Bala, S.S. Bashir, Abdulhadi M (2018). Chemical and pharmaceutical properties of pefloxacin: a review. Indian research journal of pharmacy and science, 5 (2): 1427-1431.

28-    Mohamad M J Mohamad, Mustafa Al-Shehabat, Issa Ahmad AlShehabat, Ahed J Alkhatib (2018). The variations in altitude predict angiotensin ii and blood pressure variables in Jordan. Indian research journal of pharmacy and science, 5 (2): 1449-1455.


29-    Ahed J Alkhatib (2018). New Perspectives of Autoimmunity Diseases and Microbiome: Etiology and Treatment. Acta Scientific Pharmaceutical Sciences, 2(10): 12-14.

30-    Ahed J Alkhatib (2017). White Matter and Disease: Does Brain have a Role in Initiating Diseases. Brain Disorders & Therapy, 6: e124. doi: 10.4172/2168-975X.1000e124.

Research Interest: Area of Gastrointestinal Cancer and Inflammatory Bowel Disease. 

Dr. Gorelik has nearly 35 years of experience in clinical medicine and research. He has published more than 60 scientific publications. Currently, Dr. Gorelik serves as the Head of the Department of Internal Medicine "F" in the Assaf Harofeh Medical Center, Zerifin, Israel. He is also a Clinical Senior Lecturer in the Sackler Faculty of Medicine of the Tel Aviv University.

Research Interest: Diabetes, Orthostatic Hypotension, Magnesium Metabolism, Heart Failure and Hospital Internal Medicine.

Number of Publications: 57

Research Interest: Obesity, Chronic Hronic Inflammation, Inflammatory Disease, Cancer

Research Interest: Cardiovascular Disease, Electrophysiology, Pacemaker, ICD and CRT Therapy, Metabolic Syndrome, Bidirectional Effect of CVD and CKD

Research Interest: Deep Specialization in Research Involve; Obesity and Associated Disorder, Its Mechanism and Treatment. Metabolic Syndrome-Food Additives and Its Effect on the Bodyorgans. Also the Biochemical, Oxidative Stress and Advanced Biomarkers in Health and Diseases. Recently Involved in Nanomedical Materials as Antioxidant for Health Maintainance.

Research Interest: He has Vast Experience in Characterization of New Chemical Entities (NCE’S) for Early Stage Dosage form Development, Preparation of Nano Particles, Spray Dried Powders, Solubility Screening, Bio-Availability Enhancement, Granulation and Fluid Bed Drying, Compression Using Rotary Tablet Press, Coating, Stability Studies and Tech Transfer Etc.

Research Interest: Evaluation of biological activity of plant foods: anti-inflammatory, anti-glycation, anti-oxidant activities Influences of heat treatment on biological activity of foods.

List of Publications:

1.    Ho, Su-Chen, Chang, Yi-Huang, “Comparison of inhibitory capacities of 6-, 8- and 10-gingerols/shogaols on the canonical NLRP3 inflammasome-mediated IL-1β secretion” Molecules, Vol. 23, 2018, 02, p. 466.
2.    Ho, Su-Chen, Su, Min-Sheng, Lin, Chih- Cheng, Chiu, Chui-Feng, “Comparison of anti-glycation capacity of two new purple-colored-leaf tea cultivars with an ordinary green-colored-leaf tea cultivar in Taiwan,” Global Journal of Obesity, Diabetes and Metabolic Syndrome, Vol. 4, No. 1, 2017, 02, pp. 009-015.
3.    Yang, Tzu-Ting, Ho, Su-Chen, Chuang, Lu-Te, Chuang, Hsiao-Chi, Li, Ya-Ting, Wu, Jyun-Jie, “Characterization of particulate-phase polycyclic aromatic hydrocarbons emitted from incense burning and their bioreactivity in RAW264.7 macrophage,” Environmental Pollution, Vol. 220, 2017, 01, pp. 1190-1198.
4.    Ho, Su-Chen, Su, Min-Sheng, “Optimized heat treatment enhances the anti-inflammatory capacity of ginger “ International Journal of Food Properties, Vol. 19, 2016, pp. 1884-1898.
5.    Ho, Su-Chen, Su, Min-Sheng, “Evaluating the anti-neuroinflammatory capacity of raw and steamed garlic as well as five organosulfur compounds,” Molecules, Vol. 19, No. 11, 2014, pp. 17697-17714.
6.    Ho, Su-Chen, Kuo, Chun-Ting, “Hesperidin, Nobiletin, and Tangeretin Are Collectively Responsible for the Anti-neuroinflammatory Capacity of Tangerine Peel (Citri reticulatae pericarpium)” Food and Chemical Toxicology, Vol. 71, 2014, pp. 176-182.
7.    Ho, Su-Chen, Chang, Pei-Wen, Tong, Hui-Ting, Yu, Pin-Yuan, “Inhibition of Fluorescent Advanced Glycation End-products and N-carboxymethyllysine Formation by Several Floral Herbal Infusions,” International Journal of Food Properties, Vol. 17, 2014, pp. 617-628.
8.    Ho, Su-Chen, Su, Min-Sheng, Lin, Chih-Cheng, “Comparison of Peroxynitrite-Scavenging Capacities of Several Citrus Fruit Peels,” International Journal of Food Properties, Vol. 17, 2014, pp. 111-124.
9.    Ho, Su-Chen, Chang, Ku-Shang, Lin, Chih-Cheng, “Anti-neuroinflammatory Capacity of Fresh Ginger Is Attributed Mainly to 10-Gingerol,” Food Chemistry, Vol. 141, No. 3, 2013, 12, pp. 3183-3191.
10.    Ho, Su-Chen, Chang, Ku-Shang, Chang, Pei-Wen, “Inhibition of Neuroinflammation by Cinnamon and its Main Components,” Food Chemistry, Vol. 138, No. 4, 2013, pp. 2275-2282.
11.    Ho, Su-Chen, Chang, Pei-Wen, “Inhibitory Effects of Several Spices on Inflammation Caused by Advanced Glycation Endproducts,” American Journal of Plant Sciences, Vol. 3, No. 7, 2012, pp. 995-1002.
12.    Ho, Su-Chen, Wu, Szu-Pei, Lin, Shyh-Mirn, Tang, Ya-Li, “Comparison of Anti-glycation Capacities of Several Herbal Infusions with that of Green Tea,” Food Chemistry, Vol. 122, 2010, pp. 768-744.
13.    Lin, Shih-Min, Wang, Shih-Wei, Ho, Su-Chen, Tang, Ya-Li, “Protective Effect of Green Tea (-)-Epigallocatechin-3-gallate (EGCG) Against the Monoamine Oxidase B Enzyme Activity Increase in Adult Rat Brains,” Nutrition, Vol. 26, 2010, pp. 1195-1200.
14.    Huang, Yung-Sheng, Ho, Su-Chen, “Polymethoxy Flavones Are Responsible for the Anti-inflammatory Activity of Citrus Fruit Peel,”Food Chemistry, Vol. 119, 2010, pp. 868-873.
15.    Ho, Su-Chen, Tang, Ya-Li, Lin, Shih-Min, Liew, Yih-Fong, “Evaluation of Peroxynitrite-Scavenging Capacities of Several Commonly Used Fresh Spices,” Food Chemistry, Vol. 119, 2010, pp. 1102-1107.
16.    Ho, Su-Chen, Lin, Chih-Cheng, “Investigation of Heat Treating Conditions for Enhancing the Anti-inflammatory Activity of Citrus Fruit (Citrus reticulata) Peels,”Journal of Agricultural and Food Chemistry, Vol. 56, 2008, pp. 7976-7982.
17.    Lin, Chih-Cheng, Hung, Pi-Fong, Ho, Su-Chen, “Heat Treatment Enhances the NO-suppressing and Peroxynitrite-intercepting Activities of Kumquat’s (Fortunella margarita Swingle) Peel,”Food Chemistry, Vol. 109, 2008, pp. 95-103.
18.    Ho, Su-Chen, Tsai, Tzung-Hsun, Tsai, Po-Jung, Lin, Chih-Cheng, “Protective Capacities of Certain Spices Against Peroxynitrite-mediated Biomolecular Damage,”Food and Chemical Toxicology, Vol. 46, 2008, pp. 920-928.
19.    Ho, Su-Chen, Hwang, Lucy Sun, Shen, Yi-Jane, Lin, Chih-Cheng, “Suppressive Effect of a Proanthocyanidin-rich Extract from Longan (Dimocarpus longan Lour.) Flowers on Nitric Oxide Production in LPS-Stimulated Macrophage Cells,”Journal of Agricultural and Food Chemistry, Vol. 55, No. 26, 2007, pp. 10664-10670.
20.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Ho, Su-Chen, “In vitro Inhibitory Effects of Rosemary Extracts on Growth and Glucosyltransferase Activity of Streptococcus sobrinus,” Food Chemistry, Vol. 105, 2007, pp. 311-316.
21.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Yu, Chun-Hsien, Ho, Su-Chen, “Evaluation of NO-suppressing Activity of Several Mediterranean Culinary Spices,” Food and Chemical Toxicology, Vol. 45, 2007, pp. 440-447.
22.    Tsai, Po-Jung, Tsai, Tzung-Hsun, Yu, Chun-Hsien, Ho, Su-Chen, “Comparison of NO-scavenging and NO-suppressing Activities of Different Herbal Teas with those of Green Tea,” Food Chemistry, Vol. 103, 2007, pp. 181-187.
23.    Lin, Chih-Cheng, Lu, Min-Jer, Chen, Shen-Jen, Ho, Su-Chen, “Heavy Fermentation Impacts NO-Suppressing Activity of Tea in LPS-activated RAW 264.7 Macrophages,” Food Chemistry, Vol. 98, 2006, pp. 483-489.
24.    Tsai, Tzung-Hsun, Tsai, Po-Jung, Ho, Su-Chen, “Antioxidant and Antiinflammatory Activities of Several Commonly Used Spices,” Journal of Food Science, Vol. 70, No. 1, 2005, pp. pp. C93-C97.
25.    Tsai, Po-Jung, Yu, Chun-Hsien, Hsu SP, Lee YH, Huang IT, Ho, Su-Chen, Chu CH “Maternal plasma adiponectin concentrations at 24 to 31 weeks of gestation: Negative association with gestational diabetes mellitus” Nutrition, Vol. 21, No. 11-12, 2005, pp.1095-9 •
26.    Tsai, Po-Jung, Ho, Su-Chen, Tsai LP, Lee YH, Hsu SP, Yang SP, Chu CH, Yu, Chun-Hsien, “Lack of relationship between beta3-adrenergic receptor gene polymorphism and gestational diabetes mellitus in a Taiwanese population” Metabolism, Vol. 53, No. 9, 2004, pp.1136-9.
27.    Tsai, Po-Jung, Yu, Chun-Hsien, Hsu SP, Lee YH, Chiou CH, Hsu YW, Ho, Su-Chen, Chu CH. “Cord plasma concentrations of adiponectin and leptin in healthy term neonates: positive correlation with birthweight and neonatal adiposity” Clin. Endocrinol. Vol. 61, 2004, pp. 88-93.
28.    Ho, Su-Chen, Tsai, Po-Jung, ”Comparison of the effects of "hot" and "cold" Chinese medicinal plants on the production of inflammatory mediators by RAW 264.7 cells” Journal of Food and Drug Analysis, Vol. 12, No. 2, 2004, pp. 120-127.

Research Interest: Directed Toward the Idenfication of Bioactive Compound, the Total Synthesis, and Structural Modification of Natural Products from Chinese Herds, Drug Design and Synthesis Based on Natural Lead Compounds, Mechanism Study of Natural Products, Peptide Investigation Initiated from Natural Resources, the Interface of Organic Chemistry and Cell Biology.

Research Interest: Nutrition, Obesity, Weight, Diet