Articles - Molecular and Genetic Medicine

Recent articles to be released shortly in Volume-7

Open Access Research Article Article ID: AMGM-6-110

Exome sequencing reveals a homozygous frameshift variant in CAPN3 in a Tunisian patient with a neuromuscular disorder

10.17352/amgm.000010

Published On: September 27, 2022 | Pages: 001 - 004

Author(s): Exome sequencing reveals a homozygous frameshift variant in CAPN3 in a Tunisian patient with a neuromuscular disorder

Muscular dystrophy (MD) is a heterogeneous group of diseases that cause progressive weakness and loss of muscle mass. Specific signs and symptoms begin at different ages and in different muscle groups, depending on the type of muscular dystrophy. We report here a case of a Tunisian patient suffering from a neuromuscular disorder, highly suspicious of a Limb-Girdle Mus ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat

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Open Access Short Communication Article ID: AMGM-5-109

Cytosine extensions optimize case activity for telomere length regulation: Implications for CRISPR-based therapies – A short communication

10.17352/amgm.000009

Published On: December 28, 2021 | Pages: 001 - 003

Author(s): YRKM Sai*

ORCID Logo 0000-0002-6151-5687

Telomeres are nucleoprotein structures that play a crucial role in maintaining genomic stability, and their length determines cellular lifespan. Telomere shortening is linked to cellular senescence and an increased risk of cancer. The CRISPR-Cas9 system has emerged as a tool for genome engineering and telomere length regulation. However, several factors, including chr ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat

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Open Access Mini Review Article ID: AMGM-4-108

Tumor-stroma cross talk and platelets: Curse of cancers

10.17352/amgm.000008

Published On: October 06, 2020 | Pages: 018 - 019

Author(s): Ashok Vikey*

Platelets are essential part of our vascular system, named as thrombocytes and their main role is to stop bleeding; by clumping and aggregating at damaged vascular location. Embryonically the platelets originate in bone marrow from megakaryocytes. These are smallest structures among blood cells, with average dimensions less than 4 microns in size, biconvex or straight ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat

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Open Access Review Article Article ID: AMGM-4-107

A summary of the molecular testing recommended in acute myeloid leukemia

10.17352/amgm.000007

Published On: April 18, 2020 | Pages: 012 - 017

Author(s): Ruth Stuckey, Cristina Bilbao-Sieyro and María Teresa Gómez-Casares*

Advances in Next-Generation Sequencing technologies (NGS) are revealing germline and somatic mutations that, together with karyotype, determine the diagnosis and subtype of Acute Myeloid Leukemia (AML). Molecular testing is also essential for the genetic risk stratification of patients with AML, in particular for those with normal karyotype AML (CN-AML), a large and h ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat

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Open Access Research Article Article ID: AMGM-4-106

Expression of blaCTX-M2 and invA genes of Salmonella Heidelberg isolated from poultry by Qpcr

10.17352/amgm.000006

Published On: April 16, 2020 | Pages: 006 - 011

Author(s): Gabriella Bassi das Neves, Denise Nunes Araújo, Eduarda Pick, Dinael Simão Bitner, Maiara Cristiane Brisola, Regiane Boaretto Crecencio, and Lenita Moura Stefani*

Salmonellosis is a disease caused by a bacterium Salmonella, a gram negative bacilli found in many environments, responsible for significant economic losses in poultry, and of great impact on public health. Among more than 2500 serovars, S. Heidelberg seems to be more invasive causing disease of greater severity than other serovars. The objective of this study was to ... CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat

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