Catholic University of Lyon, France
Tel: +33 4 72 32 50 36
Research Interest: Hybrid molecular imaging (PET/CT and SPECT/CT), oncology (particularly colorectal and head & Neck cancer and malignant lymphoma), criteria of response assessment after therapy (by conventional imaging and molecular imaging) and meta-analysis.
Research Interest: Lung and breast translational research, Toward personalized medicine of lung cancer: response to nontargeted therapy in invasive pulmonary adenocarcinoma as a function of tumor cell differentiation, Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma not otherwise specified) of the breast: clinicopathologic study of 19 cases, Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases, Del(5q) is associated with clinical and histological parameters in small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series.
Research Interest: I have expertise in biochemistry, molecular biology, neuro-oncology, and neuroscience. Currently, my most important areas of investigation include neuro-oncology and neurological diseases. I have been conducting research for more than 20 years in different malignant diseases of blood, breast, brain, and adrenal gland. I also conduct molecular studies in neurodegenerative disorders.
I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.
Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells
List of Publication:
Research Interest: Diagnosing and treating of various hematopathy,especially in multiple myeloma and Pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria. Therapeutic method including comprehensive treatment, drug treatment, immunological treatment and bone marrow transplantation
Research Interest: Neurofibrillary tangles composed of hyperphosphorylated tau protein accumulate in the Alzheimer’s disease and in other Neurodegenerative disease
Research Interest: CNS lymphomas, immunodeficiency associated lymphoproliferative disorders, therapy associated myeloid neoplasms and acute myeloid leukemia.
Research Interest: Cytopathology, Immunocytopathology, Molecular Cytology, Apoptosis And Oncology.
Research Interest: To analyse the cause and consequences of transbilayer movement anionic phospholipid in platelets. Anionic phospholipids, such as phosphatidylserine, are normally sequestrated in the inner leaflet of the membrane bilayer
Research Interest: 1. biologia Geral, 2. Genética, 3. Fisiologia de Órgãos e Sistemas, 4.
Research Interest: Oral cancer and molecular biomarkers of Head and Neck tumors
Research Interest: Extracellular matrix, glycosaminoglycans, hyaluronan, Inflammation – experimental models, Free radicals – oxidants and antioxidants, NF-kB pathway and cytokines, TLRs and innate immunity.
Research Interest: 1. Primary rat astroglial cells cultures. 2. Neuroblastoma and glioblastoma cells cultures. 3. Effect of antioxidant molecules [(+) thioctic acid, (+/-) thioctic acid] and choline containing compounds on proliferation and differentiation neural cell culture. 4. Study of anticancer molecules (e.g. bortezomib) and neuroprotective ones (e.g. thioctic acid) in in vitro model of neoplastic cell cultures. 5. Effect of alpha lipoic acid and choline-containing compounds, on the expression of some astroglial biomarkers during proliferation and differentiation of astrocyte cell cultures and neuroblastoma cell lines.
Research Interest: Biology, 2. Cell Biology, 3. Animal and Human Reproduction, 4. Embryonic Stem cell, 5. Virology, embryonic stem cell field, but I am also interested in Stem Cell Cytology, Cell Adhesion & Signalling and Cell Growth & Differentation
Research Interest: Design and synthesis of two-photon fluorescent dyes & sensors for biological molecules and ionic species.
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