Introduction

    • Volume/IssueClick here
    • Review ProcessYes
      • Publication lead time3 - 4 weeks
      • Indexing statusYes; Purview
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      • Waiver policy for APCYes
      • Language of Full TextEnglish
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    • Articles digitally archived in PORTICO
    • Permanent article identifierDOI (Digital Object Identifier) We provide DOI to all published papers to facilitate higher citation and classification of articles.
      Peertechz Publisher ID: 10.17352
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      • Open AccessYes; Policy
      • Does the author retain unrestricted copyright?Yes
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    Editor-in-Chief

    EXBRAYAT Jean-Marie

    EXBRAYAT Jean-Marie
    Catholic University of Lyon, France
    Email: jmexbrayat@univ-catholyon.fr
    Tel: +33 4 72 32 50 36

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    Editorial Board

    Anna Margherita Maffione
    Nuclear Medicine Consultant
    Nuclear Medicine
    Italy
    maffionemarghe@libero.it
    ACP

    Research Interest: Hybrid molecular imaging (PET/CT and SPECT/CT), oncology (particularly colorectal and head & Neck cancer and malignant lymphoma), criteria of response assessment after therapy (by conventional imaging and molecular imaging) and meta-analysis.

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    Paul H Harte
    Consultant Histopathologist
    University Hospital Galway
    Ireland
    hartelp@dhswv.org
    ACP

    Research Interest: Lung and breast translational research, Toward personalized medicine of lung cancer: response to nontargeted therapy in invasive pulmonary adenocarcinoma as a function of tumor cell differentiation, Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma not otherwise specified) of the breast: clinicopathologic study of 19 cases, Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases, Del(5q) is associated with clinical and histological parameters in small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series.

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    Swapan K Ray
    Department of Pathology, Microbiology and Immunology
    University of South Carolina
    USA
    swapan.ray@uscmed.sc.edu
    ACP

    Research Interest: I have expertise in biochemistry, molecular biology, neuro-oncology, and neuroscience. Currently, my most important areas of investigation include neuro-oncology and neurological diseases. I have been conducting research for more than 20 years in different malignant diseases of blood, breast, brain, and adrenal gland. I also conduct molecular studies in neurodegenerative disorders.

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    Juliano Andreoli Miyake
    Associate Professor
    Morphological Science Department
    Federal University of Santa Catarina
    Brazil
    juliano.miyake@ufsc.br
    ACP

    I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.

    Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells

    List of Publication:

    1. Massaro,R; Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017.
    2.  Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056.
    3.  Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11.
    4. Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,.  Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32.
    5.  Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51.
    6. Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8.
     </xml> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> Massaro,R; Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017.Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056.Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11.Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,.  Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32.Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51.Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8.  </xml> <style> /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Times New Roman","serif";} </style> Massaro,R; Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017. Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056. Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11. I. Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,.  Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32. Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51. Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8.  </xml>Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017. Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056. Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11. I. Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,.  Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32. Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51. Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8.
    More Info.
    Yuping Zhong
    Professor and Deputy Director
    Department of Hematology
    Capital Medical University
    China
    zhongyp3352@126.com
    ACP

    Research Interest: Diagnosing and treating of various hematopathy,especially in multiple myeloma and Pathogenesis and treatment of paroxysmal nocturnal hemoglobinuria. Therapeutic method including comprehensive treatment, drug treatment, immunological treatment and bone marrow transplantation

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    Suhail Rasool
    JFK medical Center Neurosciences
    Research center Edison New Jersey
    USA
    suhailrasool@hotmail.com
    ACP

    Research Interest: Neurofibrillary tangles composed of hyperphosphorylated tau protein accumulate in the Alzheimer’s disease and in other Neurodegenerative disease

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    Guldeep K Uppal
    Assistant Professor
    Department of Hematologic Pathology
    Thomas Jefferson University Hospitals
    USA
    guldeep.uppal@jefferson.edu
    ACP

    Research Interest: CNS lymphomas, immunodeficiency associated lymphoproliferative disorders, therapy associated myeloid neoplasms and acute myeloid leukemia.

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    Alexandra M Kalogeraki
    Professor
    Department of Pathology-Cytology
    University of Crete
    Greece
    kalogerakimed@yahoo.gr
    ACP

    Research Interest: Cytopathology, Immunocytopathology, Molecular Cytology, Apoptosis And Oncology.


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    Perumal Thiagarajan
    Professor
    Department of Pathology & Immunology and Medicine
    Baylor College of Medicine
    USA
    perumalt@bcm.edu
    ACP

    Research Interest: To analyse the cause and consequences of transbilayer movement anionic phospholipid in platelets.  Anionic phospholipids, such as phosphatidylserine, are normally sequestrated in the inner leaflet of the membrane bilayer

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    Claudineia Conationi da S Franco
    Associate Professor
    State University of Maringa
    Brazil
    clauconationi@gmail.com
    ACP

    Research Interest: 1. biologia Geral, 2. Genética, 3. Fisiologia de Órgãos e Sistemas, 4. Ciências Biológicas

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    Sandra Lucia Ventorin von Zeidler
    Professor
    Department of Pathology
    Federal University of Esperito Santo
    Brazil
    sandra.zeidler@ufes.br
    ACP

    Research Interest: Oral cancer and molecular biomarkers of Head and Neck tumors

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    Giuseppe Maurizio Campo
    Professor
    Department of Experimental and Clinical Medicine
    University of Messina
    Italy
    gcampo@unime.it
    ACP

    Research Interest: Extracellular matrix, glycosaminoglycans, hyaluronan, Inflammation – experimental models, Free radicals – oxidants and antioxidants, NF-kB pathway and cytokines, TLRs and innate immunity.

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    Vincenzo Bramanti
    Professor
    Department of Biomedical and Biotechnological Sciences
    University of Catania
    Italy
    v.bramanti@unict.it
    ACP

    Research Interest: 1. Primary rat astroglial cells cultures. 2. Neuroblastoma and glioblastoma cells cultures. 3. Effect of antioxidant molecules [(+) thioctic acid, (+/-) thioctic acid] and choline containing compounds on proliferation and differentiation neural cell culture. 4. Study of anticancer molecules (e.g. bortezomib) and neuroprotective ones (e.g. thioctic acid) in in vitro model of neoplastic cell cultures. 5. Effect of alpha lipoic acid and choline-containing compounds, on the expression of some astroglial biomarkers during proliferation and differentiation of astrocyte cell cultures and neuroblastoma cell lines.

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    Andrea Giannotti Galuppo
    Federal University of Rio Grande do Sul
    Brazil
    andreagalupo@yahoo.com.br
    ACP

    Research Interest: Biology, 2. Cell Biology, 3. Animal and Human Reproduction, 4. Embryonic Stem cell, 5. Virology, embryonic stem cell field, but I am also interested in Stem Cell Cytology, Cell Adhesion & Signalling and Cell Growth & Differentation

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    Chibao Huang
    Professor
    Chemistry and Chemical Engineering College
    Zunyi Normal University
    China
    huangchibao@163.com
    ACP

    Research Interest: Design and synthesis of two-photon fluorescent dyes & sensors for biological molecules and ionic species. 

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    DOI Logo 10.17352/acp.000023

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    The biology of Epidermal Growth Factor Receptor (EGFR) from regulating cell cycle to promoting carcinogenesis: the state of art including treatment options

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    Published On: April 21, 2020 | Pages: 044 - 047

    Author(s): Bdioui Ahlem*, Ben Khlifa Sarra, Kaabia Ons, Missaoui Nabiha, Hmissa Sihem and Mokni Moncef
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