Research Interest: To analyse the cause
and consequences of transbilayer movement anionic phospholipid in
platelets. Anionic phospholipids, such
as phosphatidylserine, are normally sequestrated in the inner leaflet of the
membrane bilayer
Research Interest: Neurofibrillary tangles composed of hyperphosphorylated tau protein accumulate in the Alzheimer’s disease and in other Neurodegenerative disease
Department of Pathology, Microbiology and Immunology
University of South Carolina
USA
swapan.ray@uscmed.sc.edu
ACP
Research Interest: I have expertise in biochemistry, molecular biology, neuro-oncology, and neuroscience. Currently, my most important areas of investigation include neuro-oncology and neurological diseases. I have been conducting research for more than 20 years in different malignant diseases of blood, breast, brain, and adrenal gland. I also conduct molecular studies in neurodegenerative disorders.
I approached science in 1999-2000 as AFS exchange students in Atlanta GA, USA. I graduated from medical school G. d’Annunzio University, Chieti in 2007, with my research project “Evaluation of E6-E7 proteins in HPV related lesion of the cervix”. In 2008 I started working at Histopathology Dept., ASL2 Lanciano-Vasto-Chieti “SS Annunziata” Hospital, Chieti, Italy and at Histopathology Dept., “G. Bernabeo” Hospital, Ortona (CH), Italy. In 2011 I have got involved in academic activities such as teaching in clinical practice to junior doctors and medical students and I kept working on HPV related lesions and on target therapy in lung cancer.
In 2012 and 2013 I was a visitor fellow at University College London Hospital, London.
On July 2014 I finished my training in Histo/Cytopathology discussing my research project on renal pathology which is still on going. Since August 2014 I am on GMC Specialist Register.
Now I am working as Clinical Fellow in Histopathology at Royal Brompton Hospital, London focusing on cardiothoracic pathology.
Research Interest: Lung cancer, breast cancer, HPV related disease and IgA nephropathy.
Research Interest:Hybrid molecular imaging (PET/CT and SPECT/CT),
oncology (particularly colorectal and head & Neck cancer and malignant
lymphoma), criteria of response assessment after therapy (by conventional
imaging and molecular imaging) and meta-analysis.
Research Interest:• Pathophysiology and molecular immunology
applied to immunological research lines.• Molecular processes underlying the
interaction between receptors of the immune response, inflammation and
characterization of new anti-inflammatory molecules. • Novel therapies for
Sjögren’s syndrome autoimmune disease. • Evaluation of the pathogenic role of
autoantibodies produced in the course of autoimmune diseases. e.t.c,
Research Interest:My current areas of interest include in vitro
fertilization, ICSI, studies of human gamete, zygote and embryo morphology in
relation to their developmental ability, and chromosomal constitution (PGD,
PGS), as well as the cryopreservation of embryos and oocytes.
Department of Biomedical and Biotechnological Sciences
University of Catania
Italy
v.bramanti@unict.it
ACP
Research Interest:1. Primary rat astroglial cells cultures. 2.
Neuroblastoma and glioblastoma cells cultures. 3. Effect of antioxidant
molecules [(+) thioctic acid, (+/-) thioctic acid] and choline containing
compounds on proliferation and differentiation neural cell culture. 4. Study of
anticancer molecules (e.g. bortezomib) and neuroprotective ones (e.g. thioctic
acid) in in vitro model of neoplastic cell cultures. 5. Effect of alpha lipoic
acid and choline-containing compounds, on the expression of some astroglial
biomarkers during proliferation and differentiation of astrocyte cell cultures
and neuroblastoma cell lines.
Research Interest:Lung and breast translational research, Toward
personalized medicine of lung cancer: response to nontargeted therapy in
invasive pulmonary adenocarcinoma as a function of tumor cell differentiation,
Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma
not otherwise specified) of the breast: clinicopathologic study of 19 cases,
Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of
20 cases, Del(5q) is associated with clinical and histological parameters in
small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal
synovial sarcoma: a clinicopathologic study of 60 cases and comparison with
five prior series.
Research Interest:Biology, 2. Cell Biology, 3. Animal and Human
Reproduction, 4. Embryonic Stem cell, 5. Virology, embryonic stem cell field,
but I am also interested in Stem Cell Cytology, Cell Adhesion & Signalling
and Cell Growth & Differentation
I have completed
my PhD in Cell Biology, working with glioma cells and studying their behavior,
using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and
morphology, to study the angiogenesis response of endothelial cells in glioma,
and the role of inflammatory mediators. After this, I did a post-doctoral
period in Spain, where I worked with artificial skin and stem cells. I did
other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer)
worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I
am an Associated Professor in Histology at Federal University of Santa
Catarina- Brazil.
Research Interest:Cancer (Central nervous system and melanoma),
angiogenesis, invasion and migration of tumoral cells
List of Publication:
1. Massaro,R; Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for publication. 2017. 2. Miyake JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056. 3. Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11. 4. Garzón, JA. Miyake, M. González-Andrades, R. Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,. Wharton´s jelly stem cells. A novel cell source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013 Aug;2(8):625-32. 5. Benadiba M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51. 6. Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids Health Dis. 2009 Mar 17;8:8. </xml>
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Massaro,R;
Brohem, C; Almeida, R; Rivelli, D; Miyake, J; Colquhoun, A; Barros, S;
Engler, S. 4-nerolidylcatechol induces autophagy in human Glioblastoma
cells.; Brazilian Journal of
Pharmaceutical Sciences. Accepted for publication. 2017.Miyake
JA, Vooijs M. Tenascin-C a novel regulator of brain tumor-initiating cells
(BTIC) in glioma acts through NOTCH. Transl Cancer Res 2017;6(Suppl
6):S1054-S1056.Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6
rat glioma cell proliferation in vitro and in the orthotopic C6 model in
vivo after osmotic pump infusion. Anticancer Res. 2014 Apr;34(4):1901-11.Garzón, JA. Miyake, M. González-Andrades, R.
Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,. Wharton´s jelly stem
cells. A novel cell source for oral mucosa and skin epithelia
regeneration. Stem
cells translational medicine. 2013 Aug;2(8):625-32.Benadiba
M, Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax
expression and induces micronucleus formation in C6 glioma cells in vitro.
IUBMB Life. 2009 Mar;61(3):244-51.Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic
acid inhibits both tumour cell cycle progression and angiogenesis in the
orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin
D1, pRb, p53 and p27 protein expression. Lipids
Health Dis. 2009 Mar 17;8:8. </xml>
<style>
/* Style Definitions */
table.MsoNormalTable
{mso-style-name:"Table Normal";
mso-tstyle-rowband-size:0;
mso-tstyle-colband-size:0;
mso-style-noshow:yes;
mso-style-priority:99;
mso-style-parent:"";
mso-padding-alt:0in 5.4pt 0in 5.4pt;
mso-para-margin:0in;
mso-para-margin-bottom:.0001pt;
mso-pagination:widow-orphan;
font-size:10.0pt;
font-family:"Times New Roman","serif";}
</style>
Massaro,R; Brohem, C; Almeida, R;
Rivelli, D; Miyake, J; Colquhoun, A; Barros, S; Engler, S. 4-nerolidylcatechol
induces autophagy in human Glioblastoma cells.; Brazilian Journal of Pharmaceutical Sciences. Accepted for
publication. 2017.
Miyake JA, Vooijs M. Tenascin-C a
novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through
NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056.
Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat
glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after
osmotic pump infusion. Anticancer
Res. 2014
Apr;34(4):1901-11.
I. Garzón, JA. Miyake, M. González-Andrades, R.
Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,. Wharton´s jelly stem cells. A novel cell
source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013
Aug;2(8):625-32.
Benadiba M,
Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax
expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51.
Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic
acid inhibits both tumour cell cycle progression and angiogenesis in the
orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin
D1, pRb, p53 and p27 protein expression. Lipids
Health Dis. 2009 Mar 17;8:8. </xml>Brazilian Journal of Pharmaceutical Sciences. Accepted for
publication. 2017.
Miyake JA, Vooijs M. Tenascin-C a
novel regulator of brain tumor-initiating cells (BTIC) in glioma acts through
NOTCH. Transl Cancer Res 2017;6(Suppl 6):S1054-S1056.
Miyake JA, Benadiba M, Ribeiro G, DE Oliveira Silva D, Colquhoun A. Novel ruthenium - gamma-linolenic acid complex inhibits C6 rat
glioma cell proliferation in vitro and in the orthotopic C6 model in vivo after
osmotic pump infusion. Anticancer
Res. 2014
Apr;34(4):1901-11.
I. Garzón, JA. Miyake, M. González-Andrades, R.
Carmona, C. Carda , MC. Sánchez-Quevedo, A. Campos, M. Alaminos,. Wharton´s jelly stem cells. A novel cell
source for oral mucosa and skin epithelia regeneration. Stem cells translational medicine. 2013
Aug;2(8):625-32.
Benadiba M,
Miyake JA, Colquhoun A. Gamma-linolenic acid alters Ku80, E2F1, and bax
expression and induces micronucleus formation in C6 glioma cells in vitro. IUBMB Life. 2009 Mar;61(3):244-51.
Miyake JA, Benadiba M, Colquhoun A. Gamma-linolenic
acid inhibits both tumour cell cycle progression and angiogenesis in the
orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin
D1, pRb, p53 and p27 protein expression. Lipids
Health Dis. 2009 Mar 17;8:8.
Research Interest:Directed neural differentiation of human
ESCs/iPSCs and the potential application of cell replacement therapy for human
neurodegenerative diseases.
Research Interest:Diagnosing and treating of various
hematopathy,especially in multiple myeloma and Pathogenesis and treatment of
paroxysmal nocturnal hemoglobinuria. Therapeutic method including comprehensive
treatment, drug treatment, immunological treatment and bone marrow
transplantation
Research Interest:Mechanistic toxicology of
carcinogenic/neurotoxic substances, occupational/environmental toxicants, &
gene therapy for management • Reproductive toxicology with regard to
intra-spermatozoal signaling associated to occupational/environmental toxicants.
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