Research Interest: Neurofibrillary tangles composed of hyperphosphorylated tau protein accumulate in the Alzheimer’s disease and in other Neurodegenerative disease

I approached science in 1999-2000 as AFS exchange students in Atlanta GA, USA. I graduated from medical school G. d’Annunzio University, Chieti in 2007, with my research project “Evaluation of E6-E7 proteins in HPV related lesion of the cervix”. In 2008 I started working at Histopathology Dept., ASL2 Lanciano-Vasto-Chieti “SS Annunziata” Hospital, Chieti, Italy and at Histopathology Dept., “G. Bernabeo” Hospital, Ortona (CH), Italy. In 2011 I have got involved in academic activities such as teaching in clinical practice to junior doctors and medical students and I kept working on HPV related lesions and on target therapy in lung cancer.

In 2012 and 2013 I was a visitor fellow at University College London Hospital, London.

On July 2014 I finished my training in Histo/Cytopathology discussing my research project on renal pathology which is still on going. Since August 2014 I am on GMC Specialist Register.

Now I am working as Clinical Fellow in Histopathology at Royal Brompton Hospital, London focusing on cardiothoracic pathology.

Research Interest: Lung cancer, breast cancer, HPV related disease and IgA nephropathy.

Number of Publication: 24

Research Interest: Mechanistic toxicology of carcinogenic/neurotoxic substances, occupational/environmental toxicants, & gene therapy for management • Reproductive toxicology with regard to intra-spermatozoal signaling associated to occupational/environmental toxicants.

Research Interest: • Pathophysiology and molecular immunology applied to immunological research lines.• Molecular processes underlying the interaction between receptors of the immune response, inflammation and characterization of new anti-inflammatory molecules. • Novel therapies for Sjögren’s syndrome autoimmune disease. • Evaluation of the pathogenic role of autoantibodies produced in the course of autoimmune diseases. e.t.c,

Research Interest: To analyse the cause and consequences of transbilayer movement anionic phospholipid in platelets.  Anionic phospholipids, such as phosphatidylserine, are normally sequestrated in the inner leaflet of the membrane bilayer

Research Interest: My current areas of interest include in vitro fertilization, ICSI, studies of human gamete, zygote and embryo morphology in relation to their developmental ability, and chromosomal constitution (PGD, PGS), as well as the cryopreservation of embryos and oocytes.

Research Interest: Extracellular matrix, glycosaminoglycans, hyaluronan, Inflammation – experimental models, Free radicals – oxidants and antioxidants, NF-kB pathway and cytokines, TLRs and innate immunity.

Research Interest: Calcium signaling, next-generation sequencing, genetical disease, cancer stem cell. Thank you very much.

Research Interest: Hybrid molecular imaging (PET/CT and SPECT/CT), oncology (particularly colorectal and head & Neck cancer and malignant lymphoma), criteria of response assessment after therapy (by conventional imaging and molecular imaging) and meta-analysis.

Research Interest: Lung and breast translational research, Toward personalized medicine of lung cancer: response to nontargeted therapy in invasive pulmonary adenocarcinoma as a function of tumor cell differentiation, Primary malignant fibrous histiocytoma (myxofibrosarcoma/pleomorphic sarcoma not otherwise specified) of the breast: clinicopathologic study of 19 cases, Granulomatous reaction to pneumocystis jirovecii: clinicopathologic review of 20 cases, Del(5q) is associated with clinical and histological parameters in small cell neuroendocrine lung carcinoma., Primary pulmonary and mediastinal synovial sarcoma: a clinicopathologic study of 60 cases and comparison with five prior series.

Research Interest: CNS lymphomas, immunodeficiency associated lymphoproliferative disorders, therapy associated myeloid neoplasms and acute myeloid leukemia.

Research Interest: Cytopathology, Immunocytopathology, Molecular Cytology, Apoptosis And Oncology.

I have completed my PhD in Cell Biology, working with glioma cells and studying their behavior, using cell culture, and various techniques and in vitro conditions and treatments to analyze cell responses and morphology, to study the angiogenesis response of endothelial cells in glioma, and the role of inflammatory mediators. After this, I did a post-doctoral period in Spain, where I worked with artificial skin and stem cells. I did other Postdoctoral research in Germany (DKFZ- German Centre of Research Cancer) worked with iPS cells and adoptive transfer for melanoma immunotherapy. Now I am an Associated Professor in Histology at Federal University of Santa Catarina- Brazil.

Research Interest: Cancer (Central nervous system and melanoma), angiogenesis, invasion and migration of tumoral cells

List of Publication:

Research Interest: Toxicology；Pharmacology；Natural product; Biochemistry；Pathology；Cell singing pathway; Ethnobotanical medication and food.

Research Interest: Tangential sectioning, apoptosis, Midazolam.