Carlo Massaroni was born in Anzio (Rome) in 1988.
He received the B.S. Degree in Biomedical Engineering from Università Campus Bio-Medico di Roma in December 2010. The Bachelor thesis title was "Perception Analysis of the form by the use of a numerical chessboard" and it was carried out in collaboration with the Bioinformatics Lab of the same University.
He received the M.S. Degree with highest honors in Biomedical Engineering from Università Campus Bio-Medico di Roma in December 2012. His graduation Thesis was entitled "Preliminary validation of a respiratory apparatus simulator for the assessment of metrological characteristics of a optoelectronic plethysmograph".
With his thesis he won two relevant National Price. On September he has been awarded the 2013 SIAMOC Dissertation Prize by the Italian Society of Clinical Movement Analysis (SIAMOC) in recognition of the outstanding quality of his undergraduate research. On October he has been awarded the 2013 GNB Dissertation Price by the Italian National Bioengineering Group (GNB) for outstanding contribute in the field of Rehabilitation and Prosthetics.
From April 2013 to January 2014 he worked as Biomechanical Researcher in the Unit of Rehabilitation at Scientific Institute for Research IRCCS Eugenio Medea of Conegliano (TV), as Scholarship Winner and Assignee for 2013.
He was PhD Student in Biomedical Engineering at Università Campus Bio-Medico di Roma from January 2014 to December 2016: he started working in the Laboratory of Measurements and Biomedical Instrumentation in January 2014, under the supervision of Prof. Sergio Silvestri.
In 2014 he has achieved the Professional Qualification as Industrial Engineer (Section A). He was Jury Aggregate Member as Topic expert in Biomedical Instrumentation during the State Examinations enabling the exercise of the profession of Engineer on behalf of Ordine degli Ingegneri of Rome. Section A - Industrial Section.
From February 2015 is Student Mentor for the International Biomechanics Society (ISB) in Instrumentation for Human Motion, Optoelectronic Systems and Optoelectronic Plethysmography.
On July 2015 he has been awarded the International Grant Travel Program Award by the International Society of Biomechanics (ISB) with the project "MoCBA - MOtion Capture for Breathing Assessment". MoCBA is an interdisciplinary project taking advantage of the research cooperation between the School of Sport & Exercise Sciences (SSES) at the University of Kent (Dr. Dickinson and Dr. Winter) and the School of Engineering, Research Unit of Measurement and Biomedical Instrumentation (UCBM) at the Campus Bio-Medico di Roma University. He is currently (until 22/04/2016) a Visiting PhD Student at University of Kent (Medway Campus, Kent, UK), where he is working in the Respiratory Clinic Unit.
On September 2017 he has been awarded the 2017 GNB Thesis Award by the Italian National Bioengineering Group (GNB) for outstanding contribute in the field of Biorobotics and Biomechanics.
2017 IEEE Sensor Council Travel Award (€ 1000) to attend the 2nd IEEE Sensors Summer
School on Optical Fibre Sensors at the University of Limerick, Ireland. 26th – 30th
June 2017 - Limerick, Ireland.
2016 European Society of Biomechanics (ESB) Travel Award (€ 400) to attend the 22nd
Congress of the European Society of Biomechanics (Respiratory Biomechanics
Session) - Lyon, France.
2015 International Society of Biomechanics (ISB) International Travel Grant (ITG2015) ($
2500) to fund the Research Project “MoCBA: Motion Capture for Breathing
Assessment” and to fund the foreign period of 6 months at University of Kent (UK).
Number of Publications: 43
Medical Image Analysis and
Processing Computer Simulations of
Nanoscale Systems Communications and
Mobile Computing Bioinformatics and
Computational Biology Computational Neuroscience and Vascular Flow Dynamics Biometrics
and Bio-robotics Computer Aided Diagnosis and Guided Surgerya
Medical Physics, Health
physics, Radiation detection, Technique of Radiation Therapy, Treatment
Planning in Radiation Therapy.
Berber phonetics, Automatic
Speech processing, Speech disorders Acoustic phonetics, Automatic Speech
Recognition, Speech Synthesis, Artificial Neural NetworksArabic phonetics
Research Interest: Applied research specifically in tissue engineering, biomaterials and regenerative medicine. Currently focus is bionanomedicine, bionanocomposites and bionanotechnology
Research Interest: Electroporation, Electroloading,
Electrochemotherapy, Drug and Gene Delivery Systems, Molecular Imaging (EPR
imaging; optical imaging; multimodal imaging – MRI/EPR, MRI/optical), Cancer
Research Interest: Design, fabrication, and optical
properties of nanomaterials,- Biomedical applications (biosensing, bioimaging,
therapy) of nanomaterials ,- Surface-enhanced Raman scattering and related
Research Interest: His research focuses on computer
assisted surgery, including medical image analysis, surgical navigation,
surgery simulation, surgical robots, biomedical manufacturing, etc.
Research Interest: Designing and preparing new nanobiomaterials Characterizing
physical and chemical properties, biocompatibility and bioactivity of the
Research Interest: Cell Printing, Now, he is especially
interested in the novel cell printing method. With the different own designed
cell printers, the project about how to printing vessels and the organ at the
same time is underway. Organ on a chip, Now, he is especially interested in
designing new method to 3D printing microfluidic chips which can be used in cell
culture and the prototype of organ
Research Interest: His research interests concentrate on the
biosensors (e.g. living cell sensor, DNA sensor and protein sensor) and BioMEMS
Research Interest: His research interests concentrate on the
biosensors (e.g. living cell sensor, DNA sensor and protein sensor) and BioMEMS
Research Interest: Biofabrication, Selective laser sintering, Nanotechnology,
3D Printing Biomaterials, Tissue Engineering
Research Interest: Biomedical
instrumentation, Health monitoring
system, System modeling
and control, robotics
Research Interest: Non-point source, soil heavy metal, absorbing Material, and restoration
Dr. Rajasekharredy Pala is a Nano biotechnologist specialized in the synthesis of various metal and metal oxide nanoparticles with their application as drug delivery agents to the primary cilia. After his post-graduation he was selected for ICMR-Senior Research Fellowship under Biomedical Sciences in 2011 and during this period of his doctoral studies at CSIR-Indian Institute of Chemical Technology, India, he has earned handsome experience on the physical and chemical characterizations techniques of nanoparticles that are enveloped with various biologically active compounds such as protein, lipids and small molecular drugs for their biomedical applications. Dr. Pala working as a research associate in Chapman University and University of California Irvine from 2015.
Research Interest: Nanomedicine, Hypertension, Cancer, Renal diseases
Skype ID: raaja.biotech
List of Publications:
Rajasekharreddy Pala, Ashraf M. Mohieldin, Kiumars Shamloo, Rinzhin T. Sherpa, Sarmed H.
Kathem, Jing Zhou, Zhongyue Luan, Jian-Guo Zheng, Amir Ahsan, and Surya M. Nauli.
Personalized Nanotherapy by Specifically Targeting Cell Organelles To Improve Vascular
Hypertension. Nano Letters Article ASAP DOI: 10.1021/acs.nanolett.8b04138
2. Zeng, Y., Zhu, J., Wang, J., Parasuraman, P., Busi, S., Nauli, S. M., Wáng, Y., Pala,
Rajasekharreddy, Liu, G. (2018). Functional probes for cardiovascular molecular
imaging. Quantitative imaging in medicine and surgery, 8(8), 838-852 (co-corresponding
3. Pala, Rajasekharreddy., Jamal, M., Alshammari, Q., Nauli, S.M. The Roles of Primary Cilia in
Cardiovascular Diseases. Cells 2018, 7, 233. (Published as cover page)
4. Rajasekharreddy Pala, Yun Zeng, Subhaswaraj Pattnaik, Siddhardha Busi, Alomari Nedaa,
Nauli Surya M, Gang Liu, (2018). Functionalized Silver Nanoparticles for Sensing, Molecular
Imaging and Therapeutic Applications. Current Nanomedicine, Pages 1 - 17 (17).
5. Pala Rajasekharreddy, Pathipati Usha Rani, Mattapally Saidulu & Sanjay K. Banerjee (2017).
Ultra-small silver nanoparticles induced ROS activated Toll-pathway against Staphylococcus
aureus disease in silkworm model, Materials Science and Engineering: C, 77, 990-1002
6. Pala Rajasekharreddy, Chao Huang, Siddhardha Busi, Jobina Rajkumari, Ming-Hong Tai, Gang
Liu (2017). Green Synthesized Nanomaterials as Theranostic Platforms for Cancer Treatment:
Principles, Challenges and the Road Ahead. Current Medicinal Chemistry, 24, 1-17. Doi.
7. Jobina Rajkumari, Siddhardha Busi, Aneesh Cherukunnel Vasu, Pala Rajasekharreddy (2017),
Facile green synthesis of baicalein fabricated gold nanoparticles and their antibiofilm activity
against Pseudomonas aeruginosa PAO1. Microbial Pathogenesis, 107: 261-269.
8. Rajasekharreddy Pala, Nedaa Alomari, Surya M. Nauli (2017). Primary Cilium-Dependent
Signaling Mechanisms, International Journal of Molecular Sciences, 18, 2272.
9. Kiumars Shamloo, Juan Chen, Jasmine Sardar, Rinzhin T. Sherpa, Rajasekharreddy
Pala, Kimberly F. Atkinson,William J. Pearce, Lubo Zhang, Surya M. Nauli (2017). Chronic
Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys.
Frontiers in Physiology, 8: 677.
10. Nauli, Surya M., Rajasekharreddy Pala, and Steven J. Kleene (2016). "Calcium channels in
primary cilia." Current Opinion in Nephrology and Hypertension 25 (5): 452-458.
11. Pala Rajasekharreddy and Pathipati Usha Rani (2014). Biofabrication of Ag nanoparticles using
Sterculia foetida L. seed extract and their toxic potential against mosquito vectors and HeLa
cancer cells. Materials Science and Engineering: C, 39, 203-212.
12. Pala Rajasekharreddy and Pathipati Usha Rani (2014). Biosynthesis and characterization of Pd
and Pt nanoparticles using Piper betle L. plant in a photoreduction method. Journal of Cluster
Science, 25: 1377-1388.
13. Praveen Kumar Kalavagunta, Rajasekharreddy Pala, Usha Rani Pathipati and Narender Ravirala
(2014). Identification of β-Naphthol derivatives as novel antifeedants and insecticides-I. Journal
of Agricultural and Food Chemistry, 62, 6571−6576.
14. Pala Rajasekharreddy and Pathipati Usha Rani (2012) Nontoxic effects of biologically
synthesized silver nanoparticles on silkworm, Bombyx mori L. Hexapoda 19 (1): 74–78.
Pathipati Usha Rani and Pala Rajasekharreddy (2011) Green synthesis of silver-protein (core–
shell) nanoparticles using Piper betle L. leaf extract and its ecotoxicological studies on Daphnia
magna. Colloids and Surfaces A: Physicochemical and Engineering Aspects. 389 (1-3): 188-194.
16. Pathipati Usha Rani, Pala Rajasekharreddy and Kommu Nagaiah (2011). Allelopathic effects of
(2n-octylcycloprop-1-enyl)-octanoic acid (I) against Four Major Weeds. Allelopathy Journal. 28
17. Pala Rajasekharreddy, Pathipati Usha Rani and Bojja Sreedhar (2010). Qualitative assessment of
silver and gold nanoparticle synthesis in various plants: a photobiological approach. Journal of
Nanoparticle Research, 12: 1711-1721.
18. Pala Rajasekharreddy and Pathipati Usha Rani (2010). Toxic properties of certain botanical
extracts against three major stored product pests. Journal of Biopesticides. 3(3): 586-589.
19. Pathipati Usha Rani and Pala Rajasekharreddy (2010). Insecticidal activity of (2n-octylcycloprop-
1-enyl)-octanoic acid (I) against three coleopteran stored product insects from Sterculia foetida
(L.). Journal of Pest Science, 83(3); 273-279.
20. Pathipati Usha Rani and Pala Rajasekharreddy (2009). Toxic and antifeedant activities of Sterculia
foetida (L.) seed crude extract against Spodoptera litura (F.) and Achaea janata (L.). Journal of
Biopesticides 2(2): 161-164.
Pathipati Usha Rani and Pala Rajasekharreddy (2013). Plants: The green factories for synthesis
of nanomaterials” in the book “Nanotechnology Environment” Edited by J.N. Govil. Studium Press
A method for isolation of an Ortho Quinone Methide intermediate. Pala Rajasekharreddy
and K.P Kumar and (PCT/IB2015/057628), WIPO publication no. WO/2016/059511.
• Green synthesis of highly monodispersed silver nanoparticles by plant. P. Usha Rani and Pala
Rajasekharreddy (File No. 4020/DEL/2012).
• Novel synthesis of 2-aminobenzothiazolomethyl naphthol derivatives and their
antifeedant activity. KP Kumar, Pala Rajasekharreddy, V. Narendar & P. Usha Rani (File No
technology; Stochastic Optical Reconstruction Microscopy(STORM); Cell Imaging
and Structure; Propagation and Scattering of Light in Random and Complex Media;
Classical Coherence Theory; Laser Communications and LaserRadar Systems;
Near-field Scattering; Optical Imaging System
Image / signal processing,
Machine learning, Computer-aided clinical diagnosis and treatment selection
Optofluidics, Surface Wettability, Drug Delivery
Functional Brain Imaging, Pre-surgical
Brain Mapping, Biomedical signal and Image Processing, Neural Engineering
My research focuses on establishing the clinical applicability of two new diagnostic parameters (to detect coronary artery disease) using a set of bench-top experiments, computational analysis, pre-clinical and clinical trials in our research group. These proposed diagnostic parameters based on fluid dynamic principles, pressure drop coefficient and lesion flow coefficient, have the potential to make a real paradigm shift in clinical decision making related to cardiovascular intervention. As part of my research involving pre-clinical and clinical trials I had collaborated with clinicians and scientists at College of Medicine, University of Cincinnati and at Cincinnati Children's Hospital and Medical Center. Preliminary results from these studies have concluded the clinical applicability of these parameters to distinguish between stenoses of various severity.
More recently, at Weill Cornell Medical College, I am working on using 3D printing, machine learning and computational fluid dynamics to predict and prevent coronary artery disease from non-invasive CCTA imaging data.
Research Interest: 3D printing, Computational fluid dynamics, clinical radiology, non-invasive CCTA scanning, machine learning, interventional cardiology, applied mathematics, bio-heat transfer
List of Publications:
1. Al'Aref SJ, Anchouche K, Singh G, Slomka PJ, Kolli KK, Kumar A, Pandey M, Maliakal G, van Rosendael AR, Beecy AN, Berman DS, Leipsic J, Nieman K, Andreini D, Pontone G, Schoepf UJ, Shaw LJ, Chang HJ, Narula J, Bax JJ, Guan Y, Min JK. Clinical applications of machine learning in cardiovascular disease and its relevance to cardiac imaging. Eur Heart J. 2018. Epub 2018/07/31. doi: 10.1093/eurheartj/ehy404. PubMed PMID: 30060039. Available from: https://www.ncbi.nlm.nih.gov/pubmed/30060039.
2. Kolli KK, Min JK. Image-based computational fluid dynamic analysis for surgical planning of sequential grafts in coronary artery bypass grafting. Accepted as Contributed full paper for publication in Conference Proceedings for IEEE Engineering in Medicine and Biology Society Conference. 2018. [Accepted]
3. van Rosendael AR, Maliakal G, Kolli KK, Beecy A, Al'Aref SJ, Dwivedi A, Singh G, Panday M, Kumar A, Ma X, Achenbach S, Al-Mallah MH, Andreini D, Bax JJ, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, Pontone G, Raff GL, Rubinshtein R, Shaw LJ, Villines TC, Gransar H, Lu Y, Jones EC, Pena JM, Lin FY, Min JK. Maximization of the usage of coronary CTA derived plaque information using a machine learning based algorithm to improve risk stratification; insights from the CONFIRM registry. J Cardiovasc Comput Tomogr. 2018;12(3):204-9. Epub 2018/05/14. doi: 10.1016/j.jcct.2018.04.011. PubMed PMID: 29753765. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29753765.
4. Singh G, Al'Aref SJ, Van Assen M, Kim TS, van Rosendael A, Kolli KK, Dwivedi A, Maliakal G, Pandey M, Wang J, Do V, Gummalla M, De Cecco CN, Min JK. Machine learning in cardiac CT: Basic concepts and contemporary data. J Cardiovasc Comput Tomogr. 2018; 12(3):192-201. Epub 2018/05/15. doi: 10.1016/j.jcct.2018.04.010. PubMed PMID: 29754806. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29754806.
5. Beecy AN, Chang Q, Anchouche K, Baskaran L, Elmore K, Kolli KK, Wang H, Al'Aref S, Pena JM, Knight-Greenfield A, Patel P, Sun P, Zhang T, Kamel H, Gupta A, Min JK. A Novel Deep Learning Approach for Automated Diagnosis of Acute Ischemic Infarction on Computed Tomography. JACC Cardiovascular imaging. 2018. Epub 2018/05/21. doi: 10.1016/j.jcmg.2018.03.012. PubMed PMID: 29778866. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29778866.
6. Peelukhana SV, Banerjee R, van de Hoef TP, Kolli KK, Effat M, Helmy T, Leesar M, Kerr H, Piek JJ, Succop P, Back L, Arif I. Evaluation of lesion flow coefficient for the detection of coronary artery disease in patient groups from two academic medical centers. Cardiovascular Revascularization
Kranthi Kolli 6 10/05/2018Medicine. 2018;19(3 Pt B):348-54. Epub 2017/10/19. doi: 10.1016/j.carrev.2017.08.018. PubMed PMID: 29037762. Available from: https://www.ncbi.nlm.nih.gov/pubmed/29037762.
7. Han D, Starikov A, Xiong G, Hartaigh B, Granser H, Kolli KK, Lee J, Rizvi A, Baskaran L, Schulman-Marcus J, Lin FY, Min JK. Relationship between endothelial wall shear stress and high-risk atherosclerotic plaque characteristic for identification of coronary lesions that cause ischemia: A direct comparison to fractional flow reserve. Journal of the American Heart Association. 2016; 5(12). doi: 10.1161/JAHA.116.004186. PubmMed PMID: 27993831. Available from: https://www.ncbi.nlm.nih.gov/pubmed/27993831
8. Kolli KK, Min JK, Ha S, Soohoo H, Xiong G. Effect of Varying Hemodynamic and Vascular Conditions on Fractional Flow Reserve: An In Vitro Study. Journal of the American Heart Association. 2016;5(7). doi: 10.1161/JAHA.116.003634. PubMed PMID: 27364988. Available from: http://www.ncbi.nlm.nih.gov/pubmed/27364988.
9. Kolli KK, van de Hoef TP, Effat MA, Banerjee RK, Peelukhana SV, Succop P, Leesar MA, Imran A, Piek JJ, Helmy TA. Diagnostic cutoff for pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve: A patient-level analysis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2016;87(2):273-82. doi: 10.1002/ccd.26063. PubMed PMID: 26424295. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26424295.
10. Peelukhana SV, Effat M, Kolli KK, Arif I, Helmy T, Leesar M, Kerr H, Back LH, Banerjee R. Lesion flow coefficient: a combined anatomical and functional parameter for detection of coronary artery disease--a clinical study. The Journal of invasive cardiology. 2015;27(1):54-64. PubMed PMID: 25589702. Available from: http://www.ncbi.nlm.nih.gov/pubmed/25589702.
11. Peelukhana SV, Banerjee R, Kolli KK, Fernandez-Ulloa M, Arif I, Effat M, Helmy T, Kerr H. Benefit of ECG-gated rest and stress N-13 cardiac PET imaging for quantification of LVEF in ischemic patients. Nuclear medicine communications. 2015;36(10):986-98. doi: 10.1097/MNM.0000000000000352. PubMed PMID: 26225941. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26225941.
12. Peelukhana SV, Kolli KK, Leesar MA, Effat MA, Helmy TA, Arif I, Schneeberger EW, Succop P, Banerjee RK. Effect of myocardial contractility on hemodynamic end points under concomitant microvascular disease in a porcine model. Heart and vessels. 2014;29(1):97-109. doi: 10.1007/s00380-013-0355-9. PubMed PMID: 23624760. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23624760.
13. Peelukhana SV, Kerr H, Kolli KK, Fernandez-Ulloa M, Gerson M, Effat M, Arif I, Helmy T, Banerjee R. Benefit of cardiac N-13 PET CFR for combined anatomical and functional diagnosis of ischemic coronary artery disease: a pilot study. Annals of nuclear medicine. 2014;28(8):746-60. doi: 10.1007/s12149-014-0869-y. PubMed PMID: 24950752. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24950752.
14. Kolli KK, Helmy TA, Peelukhana SV, Arif I, Leesar MA, Back LH, Banerjee RK, Effat MA. Functional diagnosis of coronary stenoses using pressure drop coefficient: a pilot study in humans. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2014;83(3):377-85. doi: 10.1002/ccd.25085. PubMed PMID: 23785016. Available from: http://www.ncbi.nlm.nih.gov/pubmed/23785016.
15. Kolli KK, Effat MA, Peelukhana SV, Succop P, Back LH, Leesar MA, Helmy TA, Imran A, Banerjee RK. Hyperemia-free delineation of epicardial and microvascular impairments using a basal index. Annals of biomedical engineering. 2014;42(8):1681-90. doi: 10.1007/s10439-014-1020-x. PubMed PMID: 24806315. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24806315.
Kranthi Kolli 7 10/05/2018
16. Kolli KK, Arif I, Peelukhana SV, Succop P, Back LH, Helmy TA, Leesar MA, Effat MA, Banerjee RK. Diagnostic performance of pressure drop coefficient in relation to fractional flow reserve and coronary flow reserve. The Journal of invasive cardiology. 2014;26(5):188-95. PubMed PMID: 24791716. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24791716.
17. Kolli KK, Paul AK, Back LH, Effat MA, Banerjee RK. Optimization of balloon obstruction for simulating equivalent pressure drop in physiological stenoses. Biorheology. 2013;50(5-6):257-68. doi: 10.3233/BIR-130640. PubMed PMID: 24398608. Available from: http://www.ncbi.nlm.nih.gov/pubmed/24398608.
18. Peelukhana SV, Banerjee RK, Kolli KK, Effat MA, Helmy TA, Leesar MA, Schneeberger EW, Succop P, Gottliebson W, Irif A. Effect of heart rate on hemodynamic endpoints under concomitant microvascular disease in a porcine model. American journal of physiology Heart and circulatory physiology. 2012;302(8):H1563-73. doi: 10.1152/ajpheart.01042.2011. PubMed PMID: 22287585. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22287585.
19. Kolli KK, Banerjee RK, Peelukhana SV, Effat MA, Leesar MA, Arif I, Schneeberger EW, Succop P, Gottliebson WM, Helmy TA. Effect of changes in contractility on pressure drop coefficient and fractional flow reserve in a porcine model. The Journal of invasive cardiology. 2012;24(1):6-12. PubMed PMID: 22210582. Available from: http://www.ncbi.nlm.nih.gov/pubmed/22210582.
20. Rajabi-Jaghargh E, Kolli KK, Back LH, Banerjee RK. Effect of guidewire on contribution of loss due to momentum change and viscous loss to the translesional pressure drop across coronary artery stenosis: an analytical approach. Biomedical engineering online. 2011;10:51. doi: 10.1186/1475-925X-10-51. PubMed PMID: 21658283; PMCID: 3141581. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21658283.
21. Kolli KK, Banerjee RK, Peelukhana SV, Helmy TA, Leesar MA, Arif I, Schneeberger EW, Hand D, Succop P, Gottliebson WM, Effat MA. Influence of heart rate on fractional flow reserve, pressure drop coefficient, and lesion flow coefficient for epicardial coronary stenosis in a porcine model. American journal of physiology Heart and circulatory physiology. 2011;300(1):H382-7. doi: 10.1152/ajpheart.00412.2010. PubMed PMID: 20935151. Available from: http://www.ncbi.nlm.nih.gov/pubmed/20935151.
Time-domain optical brain
imaging, functional near-infrared ectroscopy,
fluorescence measurements, analyses of
an optical properties of the media, development of optical imaging systems, brain
optics, clinical applications
Tissue & organ repair and regeneration, Tissue engineering, Wound healing,
Clinical medicine, dimensional tissue equivalent models, Novel wound and scar
remediation therapies, Chinese herbal medicine, Growth factor/extracellular
matrix protein complexes, Pharmaceutical and drugs
Surgical planning and
simulation in esthetical facial surgeryTelemedicine o Biomedical engineering
Development of new
lanthanide complexes for MRI and optical imaging: synthesis, purification
(HPLC, flash chromatography) and physicochemical characterization (NMR
spectroscopy, mass spectrometry, luminescence, UV-visible, FTIR).
Dr. Mohammed Rachidi received his PhD/ Doctorate Degree in Human and Molecular Genetics (with High Honors) at the prestigious ''Pasteur Institute'' (Paris, France), in the Department of Molecular and Cellular Genetics headed by the Professor François JACOB (Nobel Prize in Physiology/Medicine), where he studied the Cellular & Molecular Mechanisms underlying Brain Morphogenesis, Visual System development, CaMKinases & Biological Clock Function in Drosophila. Dr. Rachidi extended these Molecular Genetics works to Functional Genomics at Pasteur Institute and at Center National of Research Scientific CNRS and played key fundamental roles in different collaborative research projects with prestigious laboratories in Europe, Japan & United States. Remarkably, Dr. Rachidi collaborated with the Professor Michael ROSBASH (Nobel Prize in Physiology/Medicine 2017) in the Molecular Mechanisms of 2 genes involved in Circadian Clock. Dr. Rachidi published with Professor ROSBASH this important work in the EMBO Journal Entitled : ''A New Gene encoding a putative Transcritpion Factor Regulated by the Drosophila Circadian Clock''. Postdoctoral training & Assistant Professor with Professor Nicole LeDOUARIN at the prestigious ''College De France'' & Institute of Cellular & Molecular Embryology (Paris), Dr. Rachidi studied some Chicken & Xenopus molecules acting in Bone Morphogenetic Protein BMP signaling pathways and identified their Mouse & Human homologs involved in differentiation of specific domains of neuronal progenitors, in cerebellum development and Joubert syndrome (a form of cerebellar ataxia). These experiences of Dr. Rachidi in the Molecular Genetics and in several Animal Models were extended to Human Molecular Genetics of Down syndrome (DS) & to Molecular and Cellular Mechanisms underlying Brain morphogenesis of Trisomic & Transgenic Mouse Models of DS and also of numerous stages of Embryonic & Fetal DS patients to elucidate the Neurogenetic Basis of Functional alterations Associated with Mental Retardation. Director of Research in Human Molecular Genetics, Faculty of Medicine University Paris 5 (France), with High Honours for Notable Scientific Research Contributions, Breakthroughs & Discoveries in Drosophila & Mouse & Human Molecular Genetics & Neurosciences, Dr. Rachidi has vast experiences with different Research Interests in Modern Molecular Genetics, Neuroscience & Biomedical Research. Dr. Rachidi realized numerous ''Discoveries and Innovations'' to name a few: (1) - Discovery of Quantitative Assessment of Gene [removed]QAGE) as a New Method in situ detecting Differential Overexpression of Candidate Genes for Mental Retardation in Down syndrome Brain Regions & for Other Diseases caused by Regionalized Quantitative Transcriptional Alterations for greater interpretation of functional processes driving gene expression. (2) - Discovery of New Cerebellar & Cerebral Phenotypes in Transgenic mouse in vivo Library of Human Down syndrome Critical Region. (3) - Discovery of a Novel Light Microscopy Technology as Powerful Tool in Developmental Biology & Biomedical & Neuroscience Research. (4) - Discovery of New Genes involved in Brain Morphogenesis & in Visual System development; in Biological Clock; in Learning & Memory and in Mental Retardation in Down syndrome & Joubert syndrome. (5) - Discovery of the First Proposed Model of Molecular and Cellular Mechanism Elucidating Neurogenetic and Neurocognitive Basis of Functional Impairments Associated with Mental Retardation in Down syndrome: in this Model Gene Dosage Effects on transcriptional variations and the nature of gene products and their functional relationships are explained with the different aspects of neuronal differentiation. Dr. Rachidi published numerous articles in highly Prestigious International Journals with High Impact Factor like EMBO, Genomics, DNA Research, Gene, Mechanisms of Development, Cytogenetics & Genome Research, Neuroscience Research, International Journal of Developmental Neuroscience, Cell Tissue Research, American Journal of Intellectual Developmental Disability, European Journal of Paediatric Neurology...and in numerous journals of Elsevier & Springer. He has also authored numerous Chapters & Books. Dr. Rachidi has been honoured worldwide as Invited Distinguished Speaker, Chairman or Invited Honourable Organizing Committee Member in numerous International Conferences, Seminars & Workshops in Europe, USA & Asia. Dr Rachidi received numerous Awards & Honors and He is an Editor, Associate Editor, Executive Editor & Editor in Chief in numerous International peer-reviewed Journals.
Dr. Mohammed Rachidi has vast experiences with different Research Interests in Modern Molecular Genetics, Neurosciences & Biomedical Research, to name a few : Cellular & Molecular Mechanisms underlying Brain Morphogenesis, Visual System, Biological Clock, Synaptic Protein Targeting, Synaptic Plasticity, CaMKII & CAMGUK/MAGUK, Learning and Memory. Functional Genomics & Mechanisms controlling Transposition at Cell Cycle. Transcription, Protein Translation & Virus-Like Particle Formation. Bone Morphogenetic Protein BMP signaling pathways, Mouse and Human Homeobox Genes, Cell Fate Determination and Differentiation, Neuronal Progenitors in Cerebellum development and Joubert syndrome. Trisomy 21, Intellectual Disability, Candidate Genes, Expression studies, Genotype-Phenotype Associations, Trisomic and Transgenic Mouse Models of Down syndrome, Neurogenetic and Neurocognitive Basis of Functional Impairments Associated with Intellectual Disability. Drosophila & Mouse & Human.
List of Publications:
- Rachidi, M. (2019). Pharmacotherapeutic Challenges for Rescuing Mental Retardation and Improving Brain Function in Down Syndrome. Biophamaceutics and Therapeutic Challenges, 2019, (In Press).
- Rachidi, M. (2018). The Genetic Dosage Imbalance Linked to Clinical Brain Alterations and Mental Disability in Down syndrome could be Targeted for Therapeutics Development.
Medical Journal of Clinical Trials and Case studies. 2018, 2 (5): 000150.
- Rachidi, M. (2018). The Molecular Pathogenesis of Down Syndrome-Associated Diseases and the Promising Potential Therapeutic Targets.
Clinical and Medical Investigations, 2018, Vol. 3(1), 1-2.
- Rachidi, M. (2018). Trisomy of Chromosome 21 provides a Genetic Model for the Role of Aneuploidy in Cell Cycle Alterations, Leukemia, Tumors and Cancer (In Press).
- Rachidi, M. (2016). Neurogenetic Disorders of Down Syndrome and Potential Pharmacotherapies for Mental Retardation.
American Journal of Clinical Neurology and Neurosurgery, 2016, Vol. 2, No. 4, 2016, pp. 45-49.
- Rachidi, M. (2015). Towards the Identification of Genetic Targets for Therapeutics of Intellectual Disability in Down syndrome.
J.J. Cenetics, 2015.
- Rachidi, M. and Lopes, C. (2013). Mental Retardation and Human Chromosome 21 Gene Overdosage: From Functional Genomics and Molecular Mechanisms towards Prevention and Treatment of the Neuropathogenesis of Down Syndrome.
Handbook of Neurochemistry and Molecular Neurobiology. In Genomics, Proteomics, and the Nervous System, Advances in Neurobiology, Springer Publishers 3rd Ed 2013.
- Rachidi M., Tetaria C., Lopes C. (2011). “Cell cycle alteration in Down syndrome”. In Berhardt LV. (Ed.), Advances in Medicine and Biology, 2011, Vol. 20. Nova Science Publisher.
- Rachidi, M. and Lopes, C. (2010). Molecular and Cellular Mechanisms Elucidating the Neurocognitive Basis of Functional Impairments Associated with Intellectual Disability in Down syndrome.
American Journal of Intellectual Developmental Disabilities, 2010; 115., 83-112.
- Rachidi, M. and Lopes, C. (2010). Cell Cycle Alteration in Down syndrome.
International Journal of Medical and Biological Frontiers, 2010, Volume 16, Issue 3/4, Nova Science Publishers.
- Rachidi, M. and Lopes, C. (2009). Gene Expression Regulation in Down syndrome: Dosage Imbalance Effects at Transcriptome and Proteome Levels. Handbook of Down syndrome Research, Edition Nova Science Publishers, Inc., 2009, 55-87
- Rachidi, M., Delezoide, A-L., Delabar, J.M. and Lopes, C. (2009). A quantitative assessment of gene [removed]QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions.
International Journal of Developmental Neuroscience, 2009, 27, 393-398.
- Rachidi, M., Tetaria, C., and Lopes, C. (2008). Trisomy of Human Chromosome 21 and Cell Cycle Control. In Leroy NH., Fournier NT. (Eds.): Cell Cycle Control: New Research, Nova Science Publishers, Inc., 2008, 159-189.
- Rachidi, M. and Lopes, C. (2008). Mental retardation and associated neurological dysfunctions in Down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways.
European Journal of Paediatric Neurology, 2008, 12, 168-182.
- Rachidi, M. and Lopes, C. (2008). Molecular Mechanisms of Mental Retardation in Down syndrome. Rachidi, M. and Lopes, C. (Editors), Nova Biomedical Book: Edition Nova Science Publishers, Inc., 2008, pp 1-94.
- Rachidi, M., Lopes, C.; C Vayssettes, D J. Smith, E M Rubin, J.M Delabar. (2007). New Cerebellar Phenotypes in YAC Transgenic mouse in vivo Library of Human Down syndrome Critical Region 1.
Biochemical Biophysical Research Communications, 2007, 364(3), 488-494.
- Rachidi, M. and Lopes, C. (2007). Molecular Mechanisms of Mental Retardation in Down Syndrome. In Carson MI. (Ed.): Focus on Mental Retardation Research. Nova Science Publishers, Inc. 2007, pp. 77-134.
- Rachidi, M. and Lopes, C. (2007). Mental retardation in Down syndrome: From gene dosage imbalance to molecular and cellular mechanisms.
Neuroscience Research, 2007, 59(4), 349-369.
- Rachidi, M. and Lopes, C. (2006). Differential transcription of Barhl1 homeobox gene in restricted functional domains of the central nervous system suggests a role in brain patterning.
International Journal of Developmental Neuroscience, 2006, 24(1), 35-44.
- Rachidi, M., Lopes, C., Delezoide, A.L. and Delabar, J.M. (2006). C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down Syndrome.
Cytogenetics and Genome Research, 2006, 112(1-2), 16-22.
- Lopes, C., Delezoide, A.L., Delabar, J.M. and Rachidi, M. (2006). BARHL1 homeogene, the human ortholog of the mouse Barhl1 involved in cerebellum development, shows regional and cellular specificities in restricted domains of developing human central nervous system.
Biochemical Biophysical Research Communications, 2006, 339, 296-304.
- Rachidi, M., Lopes, C., Costantine, M. and Delabar J.M. (2005). C21orf5, a new member of dopey family involved in morphogenesis, could participate to neurological alterations and mental retardation in Down syndrome.
DNA Research, 2005, 12, 203-210.
- Rachidi, M., Lopes, C., Charron, G., Delezoide, AL., Paly, E., Bloch, B. and Delabar, JM. (2005). Spatial and temporal localization during embryonic and fetal human development of the transcription factor SIM2 in brain regions altered in Down syndrome.
International Journal of Developmental Neuroscience, 2005, 23, 475-484.
- Rachidi, M., Lopes, C., Benichou, J.C., Hellio, R. and Maisonhaute, C. (2005). Virus-like particle formation in Drosophila melanogaster germ cells suggests a complex translational regulation of the retrotransposon cycle and new mechanisms inhibiting transposition.
Cytogenetics and Genome Research, 2005, 111(1), 88-95.
- Lopes, C., Chettouh, Z., Delabar, J.M. and Rachidi, M. (2003). The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice. Biochemical Biophysical Research Communications, 2003, 305, 915-924.
- Takamatsu, Y., *Nakagoshi, H., *Rachidi, M., Lopes, C. Nishida, Y. and Ohsako, S. (2002). Characterization of the dCaMKII-GAL4 driver line whose expression is controlled by the. Drosophila Ca²+/calmodulin dependent protein kinase II promoter.
Cell Tissue Research., 2002, 310(2), 237-252.
- Lopes, C., Gassanova, S., Delabar, J.M. and Rachidi, M. (2001). The CASK/Lin-2 Drosophila Homologue, Camguk, Could Play a Role in Epithelial Patterning and in Neuronal Targeting.
Biochemical Biophysical Research Communications, 2001, 284(4), 1004-1010.
- Lopes, C., Rachidi, M., Charron, G., Chamoun, Z., Dahmane, N., Toyama, K., Chettouh, Z., Vekemans, M., Bloch, B., Delezoide, A.L. and Delabar, JM. (2001). Conservation of the CNS expression pattern of new genes from the Down syndrome chromosomal region-1: human genes and their murine orthologs.
Cytogenetics and Cell Genetics, 2001, 92(1-2), 1-22.
- Rachidi, M., Lopes, C., Gassanova, S., Sinet, P.M., Vekemans, M., Attie, T., Delezoide, A.L. and Delabar, J.M. (2000). Regional and cellular specificity of TPRD, the tetratricopeptide Down Syndrome gene, during embryonic development.
Mechanisms of Development, 2000, 93(1-2), 189-193.
- Delabar, J.M., Rachidi, M., Lopes, C., Charron, G., Chamoun, Z, Dahmane, N., Toyama, K., Chettouh, Z., Vekemans, M., Bloch, B. and Delezoide, A.L. (2000). Conservation of the CNS expression pattern of new genes from the Down Syndrome Chromosomal Region-1: Human genes and their Murine orthologs.
European Journal Neuroscience, 2000, 12(Supp 11), 297.
- Orti, R., Rachidi, M., Viallard, F., Toyama, K., Lopes, C., Taudien, S., Rosenthal, A., Sinet, P.M. and Delabar, J.M. (2000). Characterisation of a novel gene, C21orf6, mapping to a critical region of chromosome 21q22.1 involved in the monosomy 21 phenotype and its murine ortholog.
Genomics, 2000, 64(2), 203-210.
- Rahmani, Z., Lopes, C., Rachidi, M. and Delabar, J.M. (1999). Expression of the mnb (dyrk) protein in adult and embryonic mouse tissues.
European Journal of Human Genetics, 1999, 7(Supp.1), 111.
- Rachidi, M., Lopes, C., Takamatsu, Y., Ohsako, S., Benichou J.C. and Delabar, J.M. (1999). Dynamic expression pattern of Ca2+/calmodulin-dependent protein kinase II gene in the central nervous system of Drosophila throughout development.
Biochemical Biophysical Research Communications, 1999, 260(3), 707-711.
- Lopes, C., Rachidi, M., Gassanova, S., Sinet, P.M. and Delabar, J.M. (1999). Developmentally regulated expression of mtprd, the murine ortholog of tprd, a gene from the Down syndrome chromosomal region 1.
Mechanisms of Development, 1999, 84(1-2), 189-193.
- Rahmani, Z., Lopes, C., Rachidi, M. and Delabar, J.M. (1998). Expression of the Mnb (dyrk) protein in adult and embryonic mouse tissues.
Biochemical Biophysical Research Communications, 1998, 253(2), 514-518.
- Rachidi, M., Lopes, C. and Benichou, J.C. (1997). Genetical analysis of visual system disorganizer (vid), a new gene involved in normal development of eye and optic lobe of the brain in Drosophila melanogaster.
Genetica, 1997, 99, 31-45.
- Rachidi, M., Lopes, C., Benichou, J.C. and Rouyer, F. (1997). Analyse of period circadian expression in the Drosophila head by in situ hybridization. Journal of Neurogenetics, 1997, 11, 255-263.
- Rouyer, F., Rachidi, M., Pikielny, C. and Rosbash, M. (1997). A new gene encoding a putative transcritpion factor regulated by the Drosophila circadian clock.
EMBO Journal, 1997, 16(13), 3944-3954.
- Haoudi, A., Rachidi, M., Kim, M.H., Champion, S., Best-Belpomme, M. and Maisonhaute, C. (1997). Developmental expression analysis of the 1731 retrotransposon reveals an enhancement of Gag-Pol frameshifting in males of Drosophila melanogaster.
Gene, 1997, 196 (1-2), 83-93.
- Fassouane, A., Rachidi, M., Rouffaud, M.A., El-Abbouyi, A. and Nguyen, V.H. (1995). In vitro antifungal activity of Bacillus licheniformis FSJ-2 products against dermatophytes.
Journal of Mycology and Medicine, 1995, 5, 244-248.
- Rachidi, M. (1993). The Drosophila visual system: An elaborated building and a powerful model for developmental studies. Biomatec Journal, 1993, 4-5, 2-8.
Acetylcholinesterase reactivators as treatment of nerve agent and pesticide
intoxications; Acetylcholinesterase inhibitors in Alzheimer´s disease and Myasthenia
Gravis treatment; Synthesis of the detergents as disinfectants, decontamination
means and environment for micellar catalysis; Drug design and Development;
Chemical warfare agents; Biological warfare agents; Pharmaceutical Industry;
Project Management; Scientific Management; Technology Transfer;
Commercialization; Fund Raising; Cloud computing; Parallel computing; medical
devices development; toxins.
Dr. Idress Hamad Attitalla, (Professor, 2015) has completed his PhD at the age of 31 years from Uppsala University (Sweden) and postdoctoral studies from USM University Sains Malaysia. I use to work as the director of Research and Study at Agriculture Research Center (ARC) up to 2014, also a Consultant and Director of European Branch at Libyan Commission for Education, Culture and Science. and Scientific Consultant, Libya and director of departments of microbiology at (Omar Al-Mukhtar University, Al-Bayda, Libyaوup to now), dean of Faculty of Mdecal Technology . He published more than 80 papers in reputed journals and serving as an editorial board member of repute, and 1 book in Arabic about Algae and 1 translated book about proteomic. I act as a Editor and Reviwers in many organization including Elsevier, with ORCID 0000-0002-1037-4837
Microbiology; Molecular Biology and Biotechnology; Biosciences; Mycology and Bacteriology; Biomedical and Life Sciences; Agriculture and Forestry; Molecular Evolution.
List Of Publications:
1. Idress H. Attitalla, S. Brishammar and S, Camyon. 1998. Effects of soil Moisture and Temperature on Incidence of Fusarium Wilt on Tomato. Journal of Mycology and Plant Pathology. 28: (3), 308-313. (ISI).
2. Idress H. Attitalla, P. Quintanilla and S. Brishammar. 1998. Induced Resistance in Tomato Plants against Fusarium Wilt Invoked by Fusarium sp, Salicylic Acid and Phytophthora cryptogea. Acta Phytopathologica et Entomologica Hungarica. 33: (1-2), 89-95. (ISI).
3. Idress H. Attitalla, P. Johnson, S. Brishammar and P. Quintanilla. 2001. Systemic Resistance to Fusarium Wilt in Tomato Induced by Phytophthora cryptogea. Journal of Phytopathology. 149, 373-380. (ISI, IF: 0.983).
4. Idress. H. Attitalla, P. Maria Johansson, Sture Brishammar and Berndt Gerhardson. 2001. Pseudomonas sp. strain MF30 suppresses Fusarium wilt of tomato in vivo. Phyopathologia Mediterranea. 40, 234-239. (ISI, IF: 1.117).
5. Idress H. Attitalla and S. Brishammar. 2002. Oxalic-Acid Elicited Resistance to Fusarium Wilt in Lycopersicon esculentum Mill. Plant Protection Science. 1, 128-131.
6. Idress H. Attitalla, Jamshid Fatehi, Jens Levenfors and Sture Brishammar. 2004. A rapid molecular method for differentiating two special forms (lycopersici and radicis-lycopersici) of Fusarium oxysporum. Mycological Research. 108 (7): 787–794. (ISI, IF 2.92).
7. Khaled, S. A., Faituri, M. Y., Idress H. Attitalla, El-Maraghy, S.S. M., and Issa, A.A. 2006. Physiology Responses of Wheat and Barley to Biofertilization. Assuit University Journal of Botany. 35 (2) 215–222. (ISI).
8. Idress H. Attitalla, I.H. Bataw, A., Borowicz, J.J. and Brishammar, S. 2007. 16S rDNA analysis for characterization of Pseudomonas sp. strain MF30 isolated from Rumex acetoclla roots in northern Sweden. Arab Journal of Biotechnology. 10 (2): 97–106. (ISI).
9. IdressAttitalla et al. 2007. Adaptation of some plant communities in Xerophytes and Halophytes in East Libya. Al-Mukhtar Journal of Sciences.16: 96–81.
10. Idress H. Attitalla, Laith K.T. Al-Ani, Muftah A. Nasib, Ibrahim A.A. Balal, Maziah Zakaria, Saad S.M. El-Maraghy and S.M. Rezaul Karim. 2010. Screening and identification of the associated fungi with commercial seeds and grains in El-Beida Governorate, Libya. World Applied Science Journal. 9 (7): 746–756. (ISI, Scopus). http://www.idosi.org/wasj/wasj9(7)/7.pdf
11. Idress H. Attitalla, Latiffah Z. and Baharuddin Salleh. 2010. Biology and partial sequencing of an endophytic Fusarium oxysporum and plant defense complex. American Journal of Biochemistry and Molecular Biology. 1: 121-144 (Scopus) http://scialert.net/qredirect.php?doi=ajbmb.2011.121.144&linkid=pdf
12. Idress H. Attitalla and Bahruddin Salleh. 2010. Improvement of Carboxymethyl cellulose, Xylanase production by alginate immobilized Trichoderma harzianum. Biotechnology. 9: 529-532 (ISI) http://scialert.net/qredirect.php?doi=biotech.2010.529.532&linkid=pdf
13. Praveen Gehlot, Idress H. Attitalla and Baharuddin Salleh. 2010. Anamorphic Fungi: An Overview. Middle East Journal of Scientific Research. 6 (3): 201–208 (ISI) http://www.idosi.org/mejsr/mejsr6(3)/1.pdf
14. Nagendra G. Babu, Phaninatha A. Sarma, Idress H. Attitalla and S.D.S. Murthy. 2010. Effect of Selected Heavy Metal Ions on the Photosynthetic Electron Transport and. Energy Transfer in the Thylakoid Membrane of the Cyanobacterium, Spirulina platensis. Academic Journal of Plant Sciences. 3 (1): 46-49. http://www.idosi.org/ajps/3(1)10/7.pdf
15. Idress H. Attitalla , Abobaker M. Alhasin, Amir H. Ghazali, Latiffah Zakaria, Ibrahim A.A. Balal and Baharuddin Salleh. 2010. Occurrence and Microbiological Characteristics of Azospirillum Strains Associated with Leguminous and Non-Leguminous Plants in Al Jabal Al Akhdar Eco-region, Libya. American-Eurasian Journal of Agricultural and Environmental Sciences. 8 (6): 617-625.(ISI)
16. Balaji Meriga, Idress H. Attitalla, Mopuri Ramgopal, Anjaneyulu Ediga and P.B. Kavi. 2010. Differential Tolerance to Aluminium Toxicity in Rice Cultivars: Involvementof Antioxidative Enzymes and Possible Role of Aluminium Resistant Locus. Academic Journal of Plant Sciences. 3 (2): 53-63.
17. Mopuri Ramgopal, Idress H. Attitalla, P.Avinash, and Meriga Balaji. 2010. Evaluation of Antilipidemic and Anti obesity efficacy of Bauhinia purpurea bark extract on Rats fed with high fat diet. Academic Journal of Plant Sciences. 3 (3): 104-107. http://www.idosi.org/ajps/3(3)10/1.pdf
18. P. Peter, A. Phaninatha Sarma, Md Azeem ul Hasan, S.D.S. Murthy and Idress H. Attitalla. 2010. Studies on the Impact of Nitrogen Starvation on the Photosynthetic Pigments Through Spectral Proprties of Cyanobacterium, Spirulina platensis;: Identification of Target Phycobiliprotein under Nitrogen Chlorosis. Botany Research International. 3 (2): 38-42.
19. E. Anjaneyulu, Idress H. Attitalla, S. Hemalatha, S. Bharath Raj and M. Balaji. 2011. An Efficient Protocol for Callus Induction and Plant Regeneration in Finger Millet (Eleusine coracana L.). World Applied Science Journal. (ISI, Scopus), 12 (7): 919-923. http://www.idosi.org/wasj/wasj12(7)/2.pdf
20. Ramgopal, Ch. Saisushma, Idress Hamad Attitalla, and Abobaker M. Alhasin. 2011. A Facile Green Synthesis of Silver Nanoparticles using Soap Nuts. Research Journal of Microbiology. (Scopus), 6 (5) 432-438. http://scialert.net/qredirect.php?doi=jm.2011.432.438&linkid=pdf
21. Armaghan Shafaei, Elham Farsi, B.M. Khadeer Ahamed, M.J. Ahmad Siddiqui, Idress Hamad Attitalla and I. Zhari. 2011. Evaluation of Toxicological and Standardization Parameters and Phytochemical Investigation of Ficus deltoidea. American Journal of Biochemistry and Molecular Biology. 1 (3): 237-243, (Scopus).http://n0143855.servername.com/qredirect.php?doi=ajbmb.2011.237.243&linkid=pdf
22. Avinash P, Idress H. Attitalla, Ramgopal M, Santhosh Ch, Balaji. 2011. M. In vitro antimicrobial and antioxidant activities of bark extracts of Bauhinia purpurea. 2011. African Journal of Biotechnology. 10 (45): 9160-9164 (ISI, IF: 0.565). http://www.academicjournals.org/AJB/PDF/pdf2011/17Aug/Avinash et al.pdf
23. Idress H. Attitalla and Abobaker M. Alhasin 2012. Traits Biologically Interacting Azospirillum lipoferum Strain R23. Advances in Biological Research. 6 (2): 87-94, 2012.(PubMed).
24. Elham Farsi, Armaghan Shafaei, Sook Yee Hor, Mohamed B. Khadeer Ahamed, Mun Fei Yam, Idress Hamad Attitalla, Mohd. Z. Asmawi, and Zhari Ismail. 2011. Correlation between enzymes inhibitory and antioxidant activities of standardized fractions of methanolic extract obtained from Ficus deltoidea leaves. African Journal of Biotechnology. 10: (67): 15184-15194. (ISI, IF: 0.565). http://www.academicjournals.org/AJB/PDF/pdf2011/31Oct/Farsi et al.pdf
25. Evueh, A. G, Okhuoya, J. A. and Osemwegie, O., and Idress Hamad Attitalla. 2011. Evaluation Phylloplane Fungi as Biocontrol Agent of Corynespora Leaf Disease of Rubber (Hevea Brasiliensis Muell. ARG.). 2011. World Journal of Fungal and Plant Biology. 2 (1): 01-05.
26. Muhammed Sarwar, Idress H. Attitalla, Mohammad Abdollahi. 2011. A Review on the Recent Advances in Pharmacological Studies on Medicinal Plants; Animal Studies are Done but Clinical Studies Needs Completing. Asian Journal of Animal and Veterinary Advances. 6 (8): 867-883. (ISI, Scopus, Impact Factor 0.869) http://scialert.net/qredirect.php?doi=ajava.2011.867.883&linkid=pdf
27. Idress H. Attitalla. 2011. Felicia muricata Leaf Extract May not Completely Safe for Oral Remedies. Asian Journal of Animal and Veterinary Advances. 6 (9): 884-885. (ISI, Scopus, Impact Factor 0.869) http://220.127.116.11/qredirect.php?doi=ajava.2011.884.885&linkid=pdf
28. Idress H. Attitalla. 2011. Pharmacological Properties of Cassia nigricans Vahl Against Human and Veterinary Diseases. Asian Journal of Animal and Veterinary Advances. 6 (9): 886-887. (ISI, Scopus, Impact Factor 0.869).
29. Idress H. Attitalla. 2011. Motivational and Educational Campaings May Enhance the Attidue 0f Blood Donors Swiftly. Trends in Applied Sciences Research. 6 (11): 1238-1240. (ISI, Scopus) http://www.scialert.net/qredirect.php?doi=tasr.2011.1238.1240&linkid=pdf
30. Muhammed Nouman Sohail, Fiaz Rasul, Asia Karim, Uzma Kanwal and Idress H. Attitalla. 2011. Plant as a Source of Natural Antiviral Agents. Asian Journal of Animal and Veterinary. 6 (12): 1125-1152. (ISI, Scopus, Impact Factor 0.869)
31. Idress H. Attitalla. 2011. Changes in the Iron Indices is Major Reason of Serum Hormone Disturbance in Thalassemia Patients. Journal of Medical Sciences. 11: 127-128. (ISI, Scopus)
32. Idress H. Attitalla. 2011. Ocimum gratissimum as an Analgesic and Hepatoprotective Plant. Insight Ethnopharmacology. 1 (2): 9-10. (ISI) http://docsdrive.com/pdfs/insightknowledge/ETHNOPHARMA-IK/2011/9-10.pdf
33. G.S. Panwar, Idress Hamad Attitalla and S.K. Guru. 2011. An Efficient in vitro Clonal Propagation and Estimation of Reserpine Content in Different Plant Parts of Rauwolfia serpentina L. American-Eurasian Journal of Agricultural and Environmental Sciences. 6 (4): 217-222.(ISI)
34. Idress H. Attitalla, Hanan M.A. El-Mesmary, Muftah A. Alhorer and Farj M. Shoaeb. 2009. Growth of the green alga Ankistrodesmus under various N/P ratios with spot light on the molecular taxonomy of its three species. Al-Mukhtar Journal of Sciences.24: 22-35.
35. Idress H. Attitalla, Mikaeel Y. Faturi, Salleh A. Kahed and Faheem A. Bin Khayal and Bataw A. Fungal and Aflatoxin Contamination of Feed stuff Samples at El-Beida and Shahat Cities, Libya. (Accepted)-Sebha University Journal (Pure and Applied Sciences).
36. Mikaeel Y. Faturi, M. Faraj M. Shoaeb., and Idress H. Attitalla. Tolerance of some Rhizobium leguminosae bv. vicia to different salt concentrations. (Accepted)-Al-Mukhtar Journal of Sciences.
37. Idress Hamad Attitalla. 2011. Anti-Colon Activity in Ethanolic Extract of Phytolacca americana. Pakistan Journal of Biological Sciences. 14: 914-915. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.914.915&linkid=pdf
38. Idress Hamad Attitalla. 2011. Aloe barbadensis Provides Antiviral Defense to Tasar Silkworm. Pakistan Journal of Biological Sciences. 14: 958-959. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.958.959&linkid=pdf
39. Idress Hamad Attitalla. 2011. Steroidal Ester of Cassia nigricans Have Antibacterial Potential. Pakistan Journal of Biological Sciences. 14: 996-997 (Review Article) (Scopus, ISI) http://docsdrive.com/pdfs/ansinet/pjbs/2011/996-997.pdfc
40. Idress Hamad Attitalla. 2011. Effect of Croton penduliflorus on Intestinal Enzymes Activities. Pakistan Journal of Biological Sciences. 14: 1128-1129. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.1128.1129&linkid=pdf
41. Idress Hamad Attitalla. 2011. Salvia verticillata Effects on Diabetes and Diabetes Complications. Pakistan Journal of Biological Sciences. 14: 1130-1131. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.1130.1131&linkid=pdf
42. Idress Hamad Attitalla. 2011. PTU Induction Provide Quick Screening of Hypo and Hyperlipidemia. Pakistan Journal of Biological Sciences. 14: 1132-1133. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.1132.1133&linkid=pdf
43. Idress Hamad Attitalla. 2011. A Wound Healer, Ampucare can Inhibits Bacterial Growth. Pakistan Journal of Biological Sciences. 14: 1126-1127. (Review Article) (Scopus, ISI) http://docsdrive.com/pdfs/ansinet/pjbs/2011/1126-1127.pdf
44. Idress Hamad Attitalla. 2011. Lentinus sp. RJ-2 Mushroom is Important Source of Natural Antioxidative Polysaccharides. Pakistan Journal of Biological Sciences. 14: 1070-1071. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.1070.1071&linkid=pdf
45. Idress Hamad Attitalla. 2011. Modified CTAB Method for High Quality Genomic DNA Extraction from Medicinal Plants. Pakistan Journal of Biological Sciences. 14: 998-999. (Review Article) (Scopus, ISI) http://scialert.net/qredirect.php?doi=pjbs.2011.998.999&linkid=pdf
46. Idress Hamad Attitalla, Suliman S. Abdelrawaf, Khawila Saeed Omar, H.M.A. El-Komy and Muhammed Sarwar, 2012. Occurrence and Microbiological Characteristics of Trichoderma in Al-Jabal Al-Akhdar Region, Libya. Journal of Biological Sciences. 12: 209-217. (Scopus, ISI)http://scialert.net/qredirect.php?doi=jbs.2012.209.217&linkid=pdf
47. Idress Hamad Attitalla and Mehmet Ozaslan, 2012. DNA Based Diagnosis of Canine Bacterial Diseases. Journal of Animal and Veterinary Advances. 11: 1954-1964. (ISI, Scopus, Impact Factor 0.869)
48. Ahmed A. Issa, Idress H. Attitalla, Hanan M. A. El-Mesmary. 2012. A first Report of Fresh Water Algae at Suluq lake, Libya. Topclass Journal of Microbiology. 1: (1) 018-024.
49. Idress Hamad Attitalla. 2012. Wuling Capsule Can Improve Cognitive and Depression Defects of Stroke. Insight Ethnopharmacology. 2: 1-2.
50. El-Dougdoug, Kh.A., A.A. Megahed, B.A. Othman , S.M. Lashin, M.A. Ibrahim, and Idress Hamad Attitalla. 2012. Induction of Salicylic Acid in Cucumber Plants Against Cucumber mosaic cucumovirus Using Biotic Inducers. American Journal of Biochemistry and Molecular Biology. 3: 248-255 (Scopus)
52. Ch.Santosh, Idress Hamad Attitalla, M.Madan Mohan. 2013. Phytochemical analysis, Antimicrobial and Antioxidant activity of Ethonolic extract of Vernonia anthelmintica. International Journal of Pharma and Bio Sciences. 4 (1): 960 - 966 (IF: 0.47) - http://www.ijpbs.net/archive-issue.php?issueid=21 (Number 96 in the list)
53. Idress Hamad Attitalla. 2013. A Bacillus spp. A Probable Source of Thermophilic α-Amylaseproduction at Industrial Scale. Insight Bacteriology. 2 (1): 1-2.http://docsdrive.com/pdfs/insightknowledge/BACTERIOL-IK/2013/1-2.pdf
54. Idress Hamad Attitalla. 2013. Lipid Related Genes Could Have a Link with the Regulation of Blood Pressure. Science International. 1: 1.
55. Muhammad Nouman Sohail, S.M.N. Amin and Idress Hamad Attitalla. 2012. PCR Based Diagnosis of Fungal Diseases in Dogs. Journal of Animal and Veterinary Advances. 11: 2804-2812. (ISI, Scopus, Impact Factor 0.869)
56. Idress Hamad Attitalla and Mehmet Ozaslan. 2012. DNA Based Diagnosis of Canine Bacterial Diseases. Journal of Animal and Veterinary Advances. 11: 1954-1964. (ISI, Scopus, Impact Factor 0.869)http://docsdrive.com/pdfs/medwelljournals/javaa/2012/1954-1964.pdf
57. Idress H. Attitalla. and Faituri, M. Y. Mass Loss and Nutrients Dynamics of Decomposing Aleppo Pine Brown Needle Litter Grown in Al-Jabel Al Akdar Ecoregion. (to be published).
58. Mohamed Younes Abdelftah Hassan1, Omar Abdelateef Omar Saad, Magda Hassan Mahran, Ahmed Ismail Madkour, Suliman S Abdelrawaf and Idress Hamad Attitalla. 2013. A new medium for screening of gram negative bacteria in portable water. International Journal of Bioassays. 2: 379-381. (ISI, Scopus, Impact Factor 3.5).
59. Idress Hamad Attitalla et al.. 2013. Prevalence of Trichoderma species in EL-Jabal EL-Akhdar region, Libya
60. Idress Hamad Attitalla. 2013. Influence of Aspergillus flavus and A.terreus on the protein contents contaminated with Aflatoxins in Peanut Seeds at Al-Bayda Governorate, Libya. (to be published).
61. Idress H. Attitalla. Some biochemical changes in Lycopersicon esculentum Mill. in response to inoculation with Phythopthora megasperma and its significance in induction of resistance against Fusarium wilt. . (to be published).
62. Norlia Mahror, Idress H. Attitalla and Baharuddin Salleh. Screening and factors stimulate gibberellic acid production by Fusarium fujikuroi. (to be published).
63. Idress H. Attitalla. Ibrahim A. A. Balal, Maziah Zakaria, Saad S.M. El-Maraghy. Detection of Aflatoxigenic fungi and Reduction of Aflatoxins in some Commercial Seeds and Grains in Al-Bayda Governorate, Libya. (to be published).
64. Idress H. Attitalla. 2010. Molecular analysis of targeted FUM1 gene for the production of FB1 in Fusarium species associated with different host plants in Malaysia. (to be published).
65. Norlia Mahror, Idress H. Attitalla and Baharuddin Salleh. Correlation between gibberellic acid production and pathogenic behavior of Fusarium fujikuroi that cause bakanae disease of rice. (to be published).
66. Idress H. Attitalla, Saber E. Mansour, Laith K.T. Al-Ani, Aeshah M. Mohammed, Mikaeel Y. Faturi, Ibrahim A. A. Balal and Saad S.M. El-Maraghy. Influence of Aspergillus flavus and Aspergillus terreus in the protein value of the two varieties of peanut grains. (Poster at the International Mycotoxin Conference to be published - held at the Park Royal Hotel, Feringgi Beach, Penang Malaysia from 1st to 4th December 2010).
Knowledge Management, Cost Benefit Analysis Method – application in company and
in medical device market development, Healthcare, efectivness of medical
mechanical properties and corrosion behaviour of biomaterials Mechanical
surface treatments (shot peening and ball-burnishing) of metals and alloys. Coatings
prior and after mechanical surface treatments. Evaluating the effects of Severe
Plastic Deformations (SPD) on the materials. Characteristics Evaluation of
surface layer properties (surface roughness, micro-hardness and residual stresses)
of metals and alloys. Fatigue, corrosion fatigue and stress corrosion cracking
of metals and alloys. Corrosion monitoring by electrochemical techniques. Analytical
assessments by SEM and EDX. Analytical assessments by spectrophotometer and
Connective Tissue, Drugs
Action, Microscopy, Protein Modeling, Bone Structure, Trace/major Elements,
Image Processing, Electromagnetism, Spectroscopy, Biometrics, Human Networks
Since 2008 Paola Saccomandi
has been involved in research activities in the fields of biomedical
instrumentations and measurements applied to medicine. From 2008 to 2011 she
worked under the supervisio of Prof. Sergio Silvestri and Dr. Emiliano Schena
in the fied of mechanical ventilation. In particular she worked on development
of optoelectronic and fiber optic-based flow sensors, as well as on ventilatory
gases humidification. In 2011 she started her main research activity in the
field of laser ablation of cancer, with particular regard to pancreatic tumor.
She developed a mathematic model aiming to predic effects of laser light o
pancreas, in terms of ablated volume and temperature distribution. Since 2012
she has been investigating the field of invasive (fiber optic sensors,
thermocouples) and non-ivasive (based on diagnostic images) thermometry for
temperature monitoring during laser ablation of tumour. In this activity she is
actively collaborating with the team of research of the Institute for
Diagnostic and Interventional Radiology of J. W. Goethe Universität Frankfurt
am Main, headed by Prof. Thomas J. Vogl. Since 2013 she has been working in the
fied of optical characterization of biological tissue, aiming to estimate
optical properties of pancreas. She is collaborating with the team of
Biophysics Institute J. W. Goethe Universität Frankfurt am Main, headed by
Prof. Werner Mäntele. In the framework of laser ablation for the removal of
pancreatic cancer, she has participated at the study approved by UCBM Ethics
Committee -ComEt UCBM-, Prot. N. 4011/2011. The study aims to treat with laser
ablation patients with inoperable pancreatic cancer. Since 2014 she is also
involved in the design and development of tactile sensors for robotic
Scaffold Design For Tissue
Engineering, Composites hydrogels For Bone Repair, Electrospinning and
Electrospraying technology, Scanning and Trasmission Electron Microscopy, Image
Analysis For Porosity Measurements, Chemical And Physical Properties
Characterization Of Composite And/Or Polymeric Substrates, Injectable Composite
Cements For Bone Cavity Filling.
Research Interest: Synthesis and characterization of inorganic and hybrid organic-inorganic nanomaterials, calcium phosphates, biomaterials, drug delivery, biomineralization and nanomedicine.
Stem cells and Regenerative
Medicine, Tissue Regeneration, Tissue Engineering Stem Cells Biology and
Differentiation, Stem cells biomaterials interaction, Mechanotransduction
fatigue, motor units, innervation zone, anal sphincter, MMG, biofeedback,
cervical kinematics, helical axis
Biophotonics and Biosensors
His current research
interests include non-linear analysis of biomedical time series, specially the
analysis of electroencephalographic and magnetoencephalographic recordings to
help physicians in the diagnosis of brain disorders
Cell and tissue engineering
Shape memory materials and
composites (bulk and thin film), Laser annealing and micro fabrication, Thin
films (characterization and materials/devices) Micro/nano mechanics, nano
patterning and indentation technology, Surface and optical properties of smart
materials. Advanced and novel materials.
Micro assembly and packaging, active
disassembly. Deployable and bi-stable structures. Materials selection Flight
mechanism in inserts Micro biomedical devices
Bone and cartilage disease
modeling, drug screening and gene correctionDirect differentiation of
pluripotent stem cells toward cartilage and boneBone reprogramming of fibroblasts
using defined factors Gene therapy for cartilage regeneration and repair in
regenerative medicine Signaling pathway of genes regulating cartilage
differentiation of human mesenchymal stem cells.Molecular basis of mesenchymal
stem cells maintaining their stemness. Stem cell biology and technique
Protein engineering and
protein chemistry, Nanobiotechnology and Protein nanocage, Biomaterials and
Biomedical engineering, Industrial microbiology
Research Interest: Basic experiment skills in molecular and cell biology, immunology and zoology as follows: Molecular biology:Regular skills of molecular biology;plasmid construction, including shRNA and overexpression, GFP fusion protein, nucleic acid extraction, purification. Biochemistry: protein expression analysis, including western blotting, immunoprecipitation and quantitative real-time RT-PCR; E.coli expressionsystem, soluble and insoluble protein purification. Cell biology: Mammalian cell culture; plasmid transfection; development of stable transfected cell lines; immunohistochemistry; immunocytochemistry. Others: Basic animal, especially mouse and rat handling skills;drosophila culture; familiar with ordinary operation of laser scanning confocal microscopy (Leica,Zeiss,Olympus), fluorescence microscopy, fluorescence spectrometer;familiar with ordinary statistic and bioinformatical softwares.
Development, Cellular and Tissue Engineering Drug and Gene Delivery, Molecular
Diagnostics Photobioreactor Design
William CS Cho
Queen Elizabeth Hospital, Hong Kong
International Journal of Immunotherapy and Cancer Research
University of Athens, Greece
Journal of Novel Physiotherapy and Physical Rehabilitation
ReGenera R&D International for Aging Intervention & San Babila Clinic, Milano, Italy
Archives of Clinical Gastroenterology
University of Pisa, Italy
Annals of Psychiatry and Treatment
Prof. Pierre Guertin
Laval University, Canada
International Journal of Pharmaceutical Sciences and Developmental Research
Hon. Pierre Guertin
Laval University, Canada
Global Journal of Obesity, Diabetes and Metabolic Syndrome
University of Siena, Italy
International Journal of Oral and Craniofacial Science
University of Siena, Italy
Archives of Renal Diseases and Management
Ohio State University, USA
Open Journal of Bioinformatics and Biostatistics
Cardiovascular Research Foundation, New York, USA
Archives of Clinical Hypertension