Cite this asMuravyev YV, Muravyeva LA, Glukhova SI, Litvinova MA (2021) Why does the new disease activity score (EgyDAS) of Rheumatoid Arthritis not function? Rheumatica Acta: Open Access 5(1): 001-002 DOI: 10.17352/raoa.000013
The analysis of almost a century-long evolution of ideas about the criteria for the activity of Rheumatoid Arthritis showed that the developed complex indices for determination there of are far from perfect, in particular the Disease Activity Score 28 (DAS28), widely used in clinical practice . Therefore, the recently developed new Disease Activity Score (EgyDAS) of Rheumatoid Arthritis  has attracted interest because it includes four laboratory markers of Rheumatoid Arthritis (RA) activity, as opposed to DAS28, which assesses only one laboratory marker. It is the authors’ opinion that EgyDAS is not only more accurate and easy to apply, but also “has both diagnostic/prognostic values in patient with RA”. Because “a subject has a low Egyscore <−0.79, he/she can be considered to not have RA disease “.
Therefore, we decided to put the new disease activity score into practice. For this purpose, a pilot study of medical documents of 9 women with RA, aged 28 to 67 years, was carried out, fulfilled the American College of Rheumatology (ACR) criteria for RA and observed in the V. A. Nasonova Research Institute of Rheumatology.
Having applied the EgyDAS offered by the authors, we have calculated the RA activity (Table 1).
• Remission ≤ −0.15;
• Low disease activity > −0.15–0.15;
• Moderate disease activity > 0.15–1.1;
• High disease activity > 1.1.
The assessment of the same RA patients in the same sequence, but according to DAS28, completed within the same period of time is represented in Table 2.
• Remission ≤ 2.6;
• Low disease activity> 2.6–3.2;
• Moderate disease activity > 3.2–5.1;
• High disease activity > 5.1
It is very unfortunate that the comparison of the results represented in Tables 1,2 allows us speaking about the impossibility of using the published EgyDAS formula in clinical practice.
Therefore, we limited the number of cases.
Hopefully, this is due to a typo in the final release of the article.
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