Cite this asBassiony AA, Gameel S (2020) The dual mobility hip arthroplasty for hip fracture in Parkinson’s disease. Open J Trauma 4(1): 032-035. DOI: 10.17352/ojt.000029
Backgroud: Patients with Parkinson’s disease are at increased risk for falls and associated hip fractures as a result of tremor, rigidity, and postural instability. The available literature is limited and conflicting regarding the optimal surgical treatment and risk for postoperative complications and mortality in this unique patient population. This study question the effectiveness of dual mobility hip arthroplasty in Parkinson’s disease patients with proximal femoral fractures.
Patients and methods: Twelve patients (13 hips) with proximal femoral fracture (fracture neck of femur in 6 cases, unstable trochanteric fracture in 5 cases and failed fixation of trochanteric fracture in 2 case). Cemented dual mobility acetabular components were used in 9 patients and a cementless dual mobility acetabular components was used in 4 patient. Follow up reports on:postoperative complication rates, in-hospital mortality, length of hospital stay, discharge status, mortality rate, recovery of prefracture ambulatory ability, and return to prefracture activities of daily living. The mean age 65 years and the mean follow-up 32 months.
Results: We did not encounter any case of dislocation of the prosthesis. Seven out of 13 patients returned to pre-fracture activities of daily living with the same disability stage while 5 patients had worsening in disability by 1 stage.
Conclusion: Dual mobility THA in the Parkinsonean patients provides both efficacy and stability with good functional results.
The prevalence of Parkinson’s disease and the incidence of hip fractures mirror an ageing population living longer [1,2]. Parkinson’s disease patients with hip fractures stay at higher risk of mortality and surgical and medical complications . Short- and long-term results in patients with Parkinson’s disease following hip fracture are generally described to be worse than in patients without this disease .
Many of these patients experience hip fracture that results in even more limitation of their mobility and may require a Total Hip Arthroplasty (THA). Postoperatively, these patients may have higher rates of dislocation or periprosthetic fractures due to PD-associated falls . As a result, orthopedic surgeons may hesitate to offer THA as a treatment to these patients. Because of advances in arthroplasty technology and the medical management of the PD, increasing numbers of PD patients undergo THA [6,7].
According to the literature, the rate of dislocation after THA in patients with PD is 0%-37% [8,9]. The neurological conditions such as neuromuscular weakness can predispose patients to gait disturbance, fall, functional disturbance, and dislocation after THA . PD patients are a high-risk group for dislocation after primary and revision THAs because of increased muscle tone and rigidity .
The available literature is limited and conflicting regarding the optimal surgical treatment and risk for postoperative complications and mortality in this unique patient population. The aim of the study was to report the clinical outcomes following dual mobility total hip arthroplasty in Parkinson’s disease patients with proximal femoral fractures.
The aim of the study was to report the clinical outcomes following dual mobility total hip arthroplasty in Parkinson’s disease patients with proximal femoral fractures.
The modified Hoehn and Yahr scale is used system for describing how the symptoms of Parkinson’s disease progress . Accordingly the patients were divided into, 2 cases (stage 1), 6 cases (stage 2) and 5 cases (stage 3) Table 1.
Twelve patients (13 hip) with proximal femoral fracture (fracture neck of femur in 6 cases, unstable trochanteric fracture in 5 cases (A2.2 and A2.3 per-trochantric according to AO classification) and failed fixation of trochanteric fracture in 2 case). The mean age 65 years and the mean follow-up 32 months (Table 2).
All 13 patients were operated using a modified lateral approach. The preservation of the gluteii, their nerve supply, and muscular attachment to the femur were of utmost importance. We preferred to suspend the gluteus medius and gluteus minimus on stay sutures and re-suture them again at the end of operation rather than to detach them from the bone. This preserves the gluteus minimus and avoids injury to the most distal branch of the superior gluteal nerve.
Cemented dual mobility acetabular components were used in 9 patients and a cementless dual mobility acetabular components was used in 4 patient .Cemented standerd femoral components were used in one patients, a cementless standerd stem was used in 7 patients, cemented long stem in 1 patients (Figure 1) and cementless revision stem was used in 4 patients
According to the patients’ general condition, immediate admission to the intensive care unit postoperatively for at least overnight observation was needed. Parenteral anticoagulation (enoxaparin—low molecular weight heparin) started 12 h postoperatively then dose adjustment and shifting to oral anticoagulant were managed in conjunction with the neurologist. All patients received prophylactic anticoagulation for at least 4 weeks. Assisted weight bearing is allowed as soon as the general condition of the patient permits under physiotherapist supervision. The figure of four positions, cross leg adduction, extreme lower limb rotations, and hip flexion of more than 100° positions were instructed to the patient’s care givers to be prohibited. Abduction pillow was advised for at least 6 weeks postoperatively.
Immediate postoperative X-ray was done for all patients to assess component alignment and stability and was repeated with every follow-up.
Follow-up was done 3 weeks postoperatively for the removal of stitches, then regularly at 6 weeks, 12 weeks then every 6 months for the first 2 years postoperatively. Examined outcomes were postoperative complication rates; in-hospital mortality; length of hospital stay; discharge status, mortality rate, recovery of prefracture ambulatory ability, and return to prefracture activities of daily living.
The operative time ranged from one and half hours to three hours with a mean blood loss of 500 cc. All the patients were discharged in average of 4 days. Two peri-prosthetic fractures had been encountered (one patient fell 2 months after total hip arthroplasty and one patient 32 months after initial surgery) and were treated operatively by wire fixation as the implant was found to be stable (Figure 2).
One late periprosthetic infection occurred 16 months postoperatively and antimicrobial suppression was chosen because comorbidities did not allow additional surgery. Throughout the whole follow-up period, urinary tract infection and chest infection were the most frequent medical complications (coincident respiratory and urinary tract infections were recorded in 5 patients) and were treated with antibiotics. No in hospital perioperative deaths occurred. One patient died with severe chest infection 6 months after surgery. We did not encounter any case of dislocation of the prosthesis. Seven out of 13 patients returned to prefracture activities of daily living with the same disability stage according to the Hoehn and Yahr classification while 5 patients had worsening in disability by 1 stage.
Parkinson’s Disease (PD) is the second most common neurodegenerative disease (after Alzheimer’s disease) with a life expectancy of 7–14 years. The motor symptoms of PD are the most prominent including bradykinesia, muscular rigidity, rest tremor, and postural and gait impairment 
Patients with Parkinson’s Disease (PD) have a heightened risk of sustaining hip fractures due to disturbed balance and gait insecurity. Most Parkinson’s disease patients experience falls as a result of disease symptoms and many have recurrent episodes . It was estimated that 60.5% of patients with Parkinson disease experience at least one episode and 39% have recurrent falls . The high frequency of falls consequently contributes to the increased fracture risk
Several studies have reported a higher risk of bone fractures in patients with Parkinson’s disease compared to the general population [14,15]. The higher risk of fracture in these patients is due to postural instability that increases the risk of fall, reduced bone mineral density due to reduced physical activity, vitamin D deficiency from lack of exposure to UV radiation and secondarily from immobilization- induced hypercalcemia .
Short- and long-term outcomes in patients with Parkinson’s disease following hip fracturee are generally considered to be worse than patients without Parkinson’s disease despite similar hospital experiences .
Although the mortality rate in patients with Parkinson’s disease undergoing surgery for fracture of the proximal femur is comparable to the general population, the morbidity is higher in these patients . Rehabilitation should be started early, as soon after postoperative stabilization of the patient in order to minimize complications and achieve the maximum degree of physical activity. According to literature, very poor results were seen after hemiarthroplasty in patients with Parkinson’s disease who were not mobilized in the first week after surgery (37% dislocation, 49% of pressure ulcers, 75% mortality) .
Dual Mobility Cups (DMCs) (also known as unconstrained tri-polar implants) are indicated in THA when the risk of instability is great especially in patients with neurological deficit. In our group of operated patients, mobilization was started on the first postoperative day and there was no case of prosthesis dislocation, which can be attributed to the implant choice,surgical technique, intensive postoperative rehabilitation, and patient’s care.
Initially the hip arthroplasty was not recommended for the treatment of femoral neck fractures in patients with Parkinson’s disease because of very high incidence of dislocation (37%) and mortality (75%). Deaths of all patients with dislocation of the prosthesis within 6 months after surgery were published by Coughlin . This observation was not confirmed in our study, but one of our patients died within 6 months after surgery for severe chest infection. Although variable mortality following hip fracture in Parkinson’s disease patients has been reported, we found it comparable with 1-year mortality published in non- Parkinson’s disease patients.
Current literature is scarce and conflicting regarding optimal surgical management, revision rate, and complications after internal fixation or prosthetic replacement of hip fractures in patients with Parkinson’s disease. Some authors have noted excessively high dislocation rates in patients treated with hemiarthroplasty, leading to the conclusion that even displaced fractures should be treated with internal fixation . However according to Karadsheh et al2015, failure of fixation for patients treated with internal fixation of non-displaced femoral neck fractures, as defined by the need for a revision operation, is significantly higher in the Parkinson’s disease compared with non-Parkinson’s (22% versus 5%; p = 0.01) .
Despite the increase in interest in the application of arthroplasty procedures in patients with PD, data on outcomes of these procedures are still relatively scarce. Therefore, this study sought to illuminate outcomes as well as rates of complications in a group of parkinsonian patients with proximal femoral fractures.
We did not encounter any case of dislocation of the prosthesis, which is often mentioned as a main complication in the literature. However, the specific complications related to the use of dual mobility hip should be noted, these are peri-prosthetic fractures in the postoperative period resulting from falls due to the neurological disease.Falls in the period after total hip arthroplasty may result in serious periprosthetic fractures of the femur as is seen in 8.3% of hip joints in our study. It is necessary for the multidisciplinary team to pay more attention to preventing falls during the postoperative period.
Dual mobility cups were efficient in reducing THA dislocations in Parkinson’s patients who are at more risk of instability due to neurologic impairment. Furthermore, they gave good functional results. Based on our findings, we recommend DM cups for all patients with a higher risk of dislocation. The dual mobility cups may give an answer to the instability issues in the patients with weaker neuromuscular control like Parkinson’s disease.
Subscribe to our articles alerts and stay tuned.