Comparison of the effectiveness of proprioceptive and isometric exercises in Patients of knee osteoarthtitis: A randomized control trail

Objective: Assessment of the effectiveness of proprioceptive and isometric exercises in patients of knee osteoarthritis (OA). Methods: The experimental study was conducted among the 40 patients who had confi rmed diagnosis of knee OA. The 40 patients were randomized into separate two groups A & B. The group A received proprioceptive exercise, whereas group B were given the isometric exercises. The data was collected before and after the treatment by using the visual analogue scale for assessing the pain intensity, whereas the analogue goniometer was used for assessing the range of motion of knee joint. After collection, the data was analyzed by using statistical packages for social sciences (Spss) version 22. Results: Patients of group A were heaving the mean age of (45.24 ± 11.52) and the patients of group B were having the mean age of (50.25 ± 12.12). Among the patients of group A, after the treatment the Knee range of motion was (113, ± 7.042), whereas among the patients of group B that was (107, ± 6.601). During the check of Vas scale, group A patients reported (4.01, ± 1.197) and group B reported (3.69, ± 1.054). Proprioceptive and isomeric exercises were statistically signifi cant (p<0.05) to fl exion range of motion and pain intensity, separately. Discussion: In current study the both exercises (proprioceptive & isometric were signifi cant in the management of Knee OA patients. Furthermore the proprioceptive exercises were found signifi cant in enhancing the range of motion of knee joint), while the isometrics gave good results in pain management. Research Article Comparison of the effectiveness of proprioceptive and isometric exercises in Patients of knee osteoarthtitis: A randomized control trail Sana Naqi1, Aadil Ameer Ali2*, Mahnoor Bugti3, Naseebullah Sheikh2, Muhammad Khan Bugti4, Shahmeer Chandio2, Amjad Hussain5, Muhammad Ishque MR5 and Taufi q Ahmad5 1Institute of Physiotherapy & Rehabilitation Sciences, Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan 2Institute of Physiotherapy & Rehabilitation sciences, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Pakistan 3Hayat Institute of Rehabilitation Medicine, Karachi, Pakistan 4Department of Physiotherapy, Shaheed Mohtarma Benazir Bhutto Institute of Trauma, Karachi, Pakistan 5Faculty of Pharmacy & Health Sciences University of Balochistan, Quetta, Pakistan Received: 10 May, 2021 Accepted: 19 May, 2021 Published: 20 May, 2021 *Corresponding author: Dr Aadil Ameer Ali, Lecturer Physiotherapy, Institute of Physiotherapy & Rehabilitation sciences, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Pakistan, Tel: +923002929464; E-mail:


Introduction
Osteoarthritis (OA) is portrayed by the breakdown of ligament in joints. A ligament crumbles; the bones of the joint start to run against each other, causing solidness and torment, which frequently debilitates development. For the most part OA harms the menisci, tendons and muscles. The bone or ligament parts may skim in the joint space, causing disturbance and explicit joint torment. Bone spikes, or osteophytes, may likewise create, causing extra torment and conceivably harm to the encompassing tissues. Osteoarthritis is named an essential and optional OA [1,2]. It most commonly affects the joints in the knee, hands, feet, spine and is also relatively common in weight bearing joints such as the knee and hip joints. Predominance OA at singular joint locales (remarkably knee, hip and hand) shows steady age-related expansions in pervasiveness. Notwithstanding, indicative OA is certainly not an unavoidable outcome of maturing. In spite of the fact that commonness of OA ascends in recurrence with age, it infl uences considerable quantities of individuals of working age. OA of the knee is more normal in women's than in men. Universally, an expected 10%-15% of grown-ups more than 60 have some level of OA [2,3]. The movements have been showed up with x-bar confi rmation in the joints of 40-60 percent of the general population past 35 years of age. This rate increments with age, coming to however much 85% in those people matured more than 75. It routinely start after the age of 40 and progress continuously, with radiographic verifi cation of the ailment present in the vast majority of the general population by 65 years of age and in around 80% of the general population age 75 years and more prepared [4]. The cause of joint pain in OA is not well understood but the basic risk factors incorporates corpulence, past knee injury or medical procedure, and word related bowing and lifting while, the Systemic danger factors incorporate factors like age, identity, sexual orientation and hereditary. Expanded age is a danger factor to expanded occurrence of OA in weight-bearing joints [5,6]. Weight has been demonstrated to be related with an expanded danger of occurrence knee OA in a few examinations. Past knee injury is likewise been advised as a contributing variable for occurrence knee OA [7]. In pharmacological management the NSAIDs are frequently being used to relieve the pain, whereas in the physiotherapy the electrotherapy (tens, ultrasound) is being used widely for the pain management, whereas the isometrics and proprioceptive Excercise are being used for the strengthening of muscles around the knee joint. Proprioceptive training is a signifi cant part of the restoration following tendon remaking. The proprioceptive preparing through stabilometry (preparing on a fl imsy board) altogether diminished scenes of the joint "giving way" [8,9]. However the Strengthing practices are essential for the strengthing of muscle around the knee joint, Furthermore the quadriceps musculature is one of the regular factors that has been seemed to impact the knee joint limits. It is clear that lower furthest point strength has a signifi cant job in knee joint stun lessening during weight bearing exercises. There is expanded danger of improvement or movement of illness because of more noteworthy or uncontrolled stacking on the joint; subsequently, quadriceps strength should be considered in the investigation of knee OA [1,10,11,12].

Study design, settings and duration
A positive randomized control study was conducted from January to June 2018, and data was collected from different

Sampling
The study was conducted on 40 patients which were randomized into two equal groups. Group A and group B. The patients of group A were given the proprioceptive exercises, whereas, the patients of group B were given the isometric exercises. Patients with both genders (male & female), age between 35-55 years , who can walk on heels and toes, suffering from symptoms more than 3 months with clinically confi rmed diagnosis of mild to moderate osteoarthritis and willing participate were included in the study. While, patient with any malignancy, above 55 years of age, with previous history of surgery , patient who had intra-articular injection or having any systemic disease which make them unable to walk or stand and not willing to sign inform consent were excluded.

Data collection procedure
Group A was receiving Proprioceptive exercises and Group B was receiving isometric exercises.. The Study was continuing for 4 weeks and a total number of 24 treatment sessions were given to each patient with 6 sessions per week. The Assessment of the patients was done at the beginning of 1st Session and at the end of treatment of 24th Session day.

Group A
In group A a set of proprioceptive exercise for 24 sessions were given continuously, which were as follows.
I. One leg balance: It included remaining on infl uenced lower extremity with loose, upstanding stance and the other leg fl exed at knee, hip and lower leg. This position was held briefl y, trailed by rest for 10 to 20 seconds, and was rehashed twice more. After a short rest, three comparative redundancies were done with the unaffected lower extrimity.it was same like one leg balance, then again, actually the member was approached to keep eyes shut while playing out the daily schedule, and afterward was rehashed twice. https://www.peertechzpublications.com/journals/journal-of-novel-physiotherapy-and-physical-rehabilitation Citation: Naqi

Group B
In Group B the Isometric quadriceps rehearses were given to individuals in long sitting circumstance with hands at side, with a piece of towel put under affected knee. The subject was by and by drew nearer to press the towel down and hold it till count of ten and subsequently loosen up and go over for 10 redundancies followed by inverse side knee. 10 emphases for each meeting. (One session per day for 24 session of treatment.)

Data analysis procedure
Descriptive statistics; categorical variables were measured as frequency and percentage where continuous variables were expressed as mean standard deviation. Data was analyzed by using Statistical Package for Social Sciences (SPSS) version 23.

Ethical concern
Approval was taken from the respective medical superintendent of hospitals. The ethical approval for this study was taken from the ethical review committee of Isra University. During study Informed patient consent was received, patients were convinced about their confi dentiality, responses and their right to withdraw anytime from study.  Figure no 1, which show that in group A patients were having mean age of (45.24+ 11.524) along with the body mass index of (30.08 + 6.844).while in group B patients having mean age of (50.25+ 12.123) along with the body mass index of (28.73 + 5.879).

Comparison of treatment (Before & After) of visual analogue
scale score and Range of motion. Table 1  The study was conducted and compared the impacts of proprioceptive and isometric activities on torment force and trouble in patients with knee osteoarthritis and discovered confl icting outcomes [11,14]. He discovered critical outcomes   huge improvement in the benchmark group (P < 0.05). At last at 3 months of treatment, improvement in relief from discomfort and knee joint capacity was seen in the experimental group than in the benchmark group, with a genuinely critical contrast (P < 0.05). These fi nding additionally reliable with the current examination that showed measurably critical upgrades in torment work in the proprioceptive gathering [17][18][19].
After that a study carried out and compared the impacts of Pilates and isometric activities on torment, useful incapacity and scope of movement in patients with knee osteoarthritis. The investigation showed stamped upgrades in torment power, practical incapacity and Lumbar ROM acquired in all the examination gatherings (Pilate practice bunch, Isometric exercise bunch and the transcutaneous electrical nerve Stimulation bunch). All result means showed huge enhancements in post-intercession. This is also consistent with the present study with improvement in pain, function and range of motion in both isometric and proprioceptive group [1,20].
Kumar et al. Investigated in his study about the impact of isometric exercise versus joined concentric-offbeat exercise preparing in patients with osteoarthritis knee. He discovered huge outcomes in Visual Analog Scale and Western Ontario and McMaster Universities Osteoarthritis Index scores in the two gatherings yet Group B was seen to be more critical better outcomes on both the scales after the treatment. Accordingly it was tracked down that isometric exercise when consolidated to concentric-fl ighty exercise preparing had more noteworthy improvement in decreasing agony and useful incapacity when contrasted with isometric activities alone [21,22]. A study conducted by Sarkar et al. to determine the Effects of obesity on quadriceps dynamic strengthening and isometrics exercise for the treatment of knee osteoarthritis patients. The results indicated that pain reduction was signifi cantly equal in both obeses and non-obese groups but range of motion was found to be more signifi cant (i.e including both fl exion and extension) in non-obese group while in group B (obese) only fl exion of the knee joint was signifi cantly improved. So It was found that the isometric exercises was more effective for non-obese patients as the greater BMI may be a factor in increasing stress at knee joint during weight bearing [3,7]. These fi nding is consistent with the present study in which isometric exercises were shown to be effective in increasing range of motion at knee joint. A study conducted and decide the Effects of isometric quadriceps muscle reinforcing exercise on persistent osteoarthritis of the knee in which agony and scope of movement of the knee joints were surveyed and followed-up week by week for about a month and a half. Improvement in the activity bunch was seen from the four weeks that expanded step by step during the treatment and toward the fi nish of about a month and a half treatment, a huge improvement was appeared in the torment and scope of movement at the knee joint [5,11,23].

Conclusion
The current study disclosed that both (Proprioceptive and Isometric) exercises had signifi cant effects on decreasing the pain and increasing the range of motion in patients with knee osteoarthritis. However the isometric exercises had shown good effects in decreasing the range of motion while proprioceptive exercises had signifi cant effects on increasing range of motion of knee joint.

Limitation
As the study was conducted among the already diagnosed patients of Knee osteoarthritis, because of that no any severity scale was used among the patients. Only Knee range of motion and Visual analogue scale was used to compare the effectiveness of exercises.