High-Diluted-Biomedicines Turmeric Extract (TE) act as Preventive Policy- Developer-Potential-21st-Century-Pandemic COVID 19 Vaccines: Achieved Community-Communication-Medicine-Science-Applications-Public-Health-Ecology-Green-Technology-Innovations–Economy-Social-Welfare-Issues!

Introduction: Recently the COVID-19 Coronavirus-Disease-2019 caused by reinfection of the numerous new-mutant-coronavirus long-COVID-19-variant SARS-CoV-2, not only effects on global health, education, clinical research, economy, prolonged-neurological-damage, and total change of human civilization, but also its effects on some organs and tissues in Children causing the ‘Multisystem-Infl ammatory-Syndrome (MIS-C)’ also, and the sixteen-months-pandemic have punctuated humanity’s timeline for hundreds of years, sowing panic, millions of infections (188) and killing 4-millions. Though the middle-and upper-classes now enjoying the vaccination, the minority, and low-income households, are really suffering. Still, the pandemic prevails, and the main objectives of the research are to fi nd out suitable cost-effective community-biomedicines or universal vaccines by using high-diluted-form of turmeric extract with the help of local students Non-Governmental-Organization (NGO), and doctors. Methods: In the 11-slam-area, the community-biomedicine of high-diluted-form, Turmeric Extract (TE) or turmeric MT, made from the turmeric-rhizome, Curcuma longa L., is mixed @10-20 drops (1-2mg) /cup (100ml-150ml) of moderately-hot germ-free-drinking-water, administered orally every-day in the early morning (with an emptystomach) once/day for thirty-days before illness-onset as a preventive measure, with no need to ethical consideration for the permissible doses and safety concerns, OR may be applied after the symptom-onset against present coronavirus infections as a vaccine, where COVID-19 patients in hospitalized, and also the dose could also be increased looking on the intensity of diseases, and age, just in case of treatment suggested by the doctors, and the young-local-students NGO, the “Burdwan-GreenHaunter-and-Students’-Goal”, take initiative for COVID-protocol, social-awarenessand treatment-camp with doctors. Results: The current preventive-treatment measures have shown that community-biomedicines of high-diluted-TE are more potent in preventing-pathogens by increasing-immunity against COVID-19 with the carcinogenic-free and ‘Multisystem-Infl ammatory-Syndrome (MIS-C)’-free results in the 11-slam treated-area than anothercontrol-area of Purba Bardhaman, and the NGOs are an active-helper in all respect. Conclusions: The easily-available, easily-suppliable, easily-applicable, side-effects-free, non-toxic, cost-effective, eco-friendly, easily-preparable, and the ‘MIS-C’ free high-diluted-potential-community-biomedicine, Turmeric Extract, maybe act as preventive-policy-developer-potential-21st-century-pandemic COVID 19 vaccine by achieving community-medicine-clinical-research-public-health-ecology-green-socio-economy-welfare-science-innovations-technology-communication-applications-issues-advancements. In new normal, it’d be the foremost important vaccines by applying the community-biomedicines of ultra-high-diluted-TE against day-to-day new virulentcoronavirus pandemics, and another multidisciplinary-health-disease suffering from COVID-19 improving community-immunity-or-herd-immunity also, and NGO act as potential-‘Social-Vaccines’ again, using biotechnology, biological researchers, biomedical-study-processes, and the fi nal goal of future developing-potential-treatments and cures. Research Article High-Diluted-Biomedicines Turmeric Extract (TE) act as Preventive PolicyDeveloper-Potential-21st-CenturyPandemic COVID 19 Vaccines: Achieved Community-Communication-MedicineScience-Applications-Public-HealthEcology-Green-Technology-Innovations– Economy-Social-Welfare-Issues! Subhas Chandra Datta* PhD & Research from Department of Zoology, VisvaBharati University, Santiniketan and Headmaster & Secretary, Kanchannagar D.N. Das High School (HS), Kanchannagar, Burdwan Municipality, Purba Bardhaman, Burdwan-713102, West Bengal, India Received: 26 July, 2021 Accepted: 13 August, 2021 Published: 14 August, 2021 *Corresponding author: Dr. Subhas Chandra Datta, PhD, Ph.D. & Research from Department of Zoology, VisvaBharati University, Santiniketan, and Headmaster & Secretary, Kanchannagar D.N.Das High School (HS), Kanchannagar, Burdwan Municipality, Purba Bardhaman, Burdwan-713102, West Bengal, India, Tel: +91 9832192464, +91 7602303924; E-mail: ORCID: https://orcid.org/0000-0002-5718-4969


Introduction
Currently, the COVID-19 coronavirus disease 2019 is caused by reinfection of the numerous new mutant-coronavirus long COVID-19 variant SARS-CoV-2, not only effects on global health, education, clinical research, economy, prolongedneurological-damage, and total change of human civilization, but also its effects on some organs and tissues in Children causing the 'Multisystem-Infl ammatory-Syndrome (MIS-C)' also, and the sixteen-months-pandemic have punctuated humanity's timeline for hundreds of years, sowing panic, millions of infections (188), and killing 4-millions. Though the middle-and upper-classes are enjoying the vaccination, the minority and low-income households are really suffering [1][2][3][4][5]. Still, the pandemic prevails, the people are asking regarding changed-research, and the scientists are navigating for the directions by developing policy initiative potential costeffective-universal-vaccines [1][2][3][4][5][6][7]. anti-apoptotic, anti-fi brotic effects, and inhibitory effects on NF-B, infl ammatory cytokines and chemokines, toll-like receptors, bradykinin, antidotal or protective effects, and its active ingredient, curcumin, are against natural and chemical toxicities [8,9]. It's reported that the potential therapeutic effect of turmeric contents against SARS-CoV-2 compared with experimental COVID-19 therapies, forming 'Wonder Drug as a safety measure for COVID19 Management' because of presence of various immune-boosting phytochemicals i.e. promising potential treatment methods or role of curcumin against this viral diseases or next promising nanosystems antiviral alternatives or the molecular mechanistic insights with relevance host-pathogen interaction and immunomodulation, and therefore the curcumin interact with S protein of SARS CoV2 and ACE2 of human plasma membrane insights from computational studies, and therefore the curcumin-piperine supplementation on clinical signs, duration, severity, and infl ammatory factors in patients with COVID-19 in a very structured summary of a study protocol for a randomised controlled trial, and it has proved the near 4000-year history of in-depth medical use in South Asia from the 'Golden Spice, Turmeric, Traditional Medicine to Modern Medicine' [10][11][12][13][14][15][16][17][18][19][20].  Therefore the purpose of the current study is to organize   high-diluted OR ultra-high-diluted cost-effective, easily prepare-able, easily available, easily manufacture-able, equitable,   marketable, and supply-able, community-biomedicine, Turmeric Extract (TE), prepared from the rhizome of turmeric, herbaceous plant, against deadly pandemic new variant and mutant-coronavirus-2 (SARS-CoV-2) patient, with the assistance of the young-energetic-local Non-Governmental-Organization (NGO) named "Burdwan Green Haunter and Students Goal", take initiative or emphasis on the employment of TE among the communities, and different activities of covid-protocol to beat this epidemic situation, and it's planned to publish as suggestions, to require preventive measures, and help policymakers and clinical scientists for community medicine vaccine discovery.
So, the specifi c, measurable, and consistent main identifi ed research objectives with designs are to fi nd out suitable costeffective community-biomedicines or universal vaccines by using high-diluted-form of turmeric extract with the help of local students Non-Governmental-Organization (NGO), and doctors."

Research design
It is the continuation of work ( Figure 1) entitled "NGO Act as Potential-Policy-Developer Social-Vaccine-COVID-19 Epidemic-Model: Achieved Green-Socio-Economic Welfare Science Technology Innovations" [21], where the specifi c, measurable, and consistent main identifi ed research objectives with designs are to fi nd out suitable cost-effective community-

Location of experiment and duration
The study was dole out by the doctors, headmaster, and young-local-Non-Governmental-Organization (NGO) named "Burdwan-Green-Haunter and Students'-Goal", at the 11slam area of Purba Bardhaman District, India. Total families were 1907 and also the total population was 12315, and therefore the activities were conducted and measured from the 11th September 2020 to 17th July 2021and up-to-date ( Figure 1 & Plate 1). All the info were counted for statistical analysis by 't'-test (P<0.01) .

Sample area
The treatment study areas were carried out by the NGO, at the 11-slam area of Burdwan Municipality and its surrounding, Purba Bardhaman, West Bengal, India, as follows:

Different activity-groups formation and function
The Burdwan Green Haunter and Students' Goal, NGO, forms four main activity-groups; core group, working group, advisory group, and social media group, headed and coordinated by the secretary, Mr. Rakesh Khan, M.A., B.Ed. (Gold Medalist), and president, Mr. Subhendu Bose, Administrator of B.Ed. College.
• Working Group-has 210-members with 11-subgroup, engaged in different social activities.
• Advisory Group-has 10-members in different disciplines like academicians, administrators, doctors, teachers, scientists, business personalities, engineers, accountant, social reformer, reporter, government employee, and entrepreneur with different-subgroup, give advice and problem solve, if necessary.
• Social-media Group-has more than 1300 members, followers 21,000, engaged mainly for publicity.
Key note: COVID-19 preventive measures rules and regulation maintained in each activity (Plate 1) .

Biomedicine turmeric extract preparation
The sun-dried and powdered sort of rhizomes-

Observations
Different behavior and attitude of the communities has been observed by NGO-direct physical access, and every one the information were counted for statistical analysis by 't'-test (P<0.01) .

Science and technology communication
The activity of students, teachers, staffs, community, photographers, visitors, and media personnel, campaign, make the news, and publication regarding the importance in Science and Technology Communication in different audiovisual media (TV channels), social media, and journals are recorded .
• Way and use and distribution of masks.
• Avoid crowded places or gatherings.
• Regular and thoroughly clean your hands with an alcohol-based sanitizer hand rub or wash with soap and water, and supply.
• Follow good respiratory hygiene.
• Way of after coughing or sneezing, dispose of the used tissue immediately and wash hands.
• Way of proper use of specifi c dustbin.
• Stay home and self-isolate even with minor symptoms such as cough, headache, mild fever, until recovery.
• If fever, cough, and diffi culty breathing, seek medical attention, but call by telephone in advance if possible and follow the directions of the local health authority.
• Keep up to date on the latest information from WHO or local and national health portal or authorities.
• Way of consuming nutritious foods and vegetables.
• Supporting maternal and child health, mental health, or initiatives against domestic violence.
• Arrangement of blood donation camp. • Tree-plantation with conservation-biodiversity.
• Procedure of reduce-economic-activities to a minimum.
• Arrangement of distributing-rations to families in slums, and to providing cooked-meals to migrants.
• Arrangement to ensuring that senior-citizens have medicines.
• Distributing clothes and educational materials.
• Mobile and digital door to door-teaching.
• Arrangement of health checkup camp.
• Arrangement of comprehensive and effective science and health consciousness and communication effort.
• Arrangement of authentic scientifi c and health information.
• The initiative is targeted at encouraging public participation in risk-related reciprocal communication processes • Involvement to build capacities and enable communities to develop a sense of awareness, an analytical mind, and a decision.
• Promote personal sanitation and hygiene, physical distancing, and maintaining desired collective behaviors, etc.
• Enhance science coverage in mass media including illustrative interpretations especially to reduce the fear of risks and build confi dence with a dose of necessary understanding.
• Inculcate scientifi c temper for adopting sustainable healthy lifestyles, and nurturing scientifi c culture among masses and societies.
• Arrangement of workshops for preparation of sanitizer and making of mask.
• Online celebration of different day.
• Arrangement of web talk on different issues.
• Arrangement of street-cornering regarding different issues emphasis on humanity in pandemic situation.
• Arrangement of different digital materials for social media.

Results and discussion
For the comparison of achievement or more success, Figure   1 is very important, and it is considered from 11/09/2020 to 17/07/2021 by using natural biomedicine of high-diluted-Tur-

Future-treatments-and-cures-of-biomedicine-turmeric
Just before submission of this paper, it's worth mentioning that it's been received the "Greetings from Advances in Agron-

Ethical approval turmeric extract
The questions may arise regarding "There is no mention of the approval from an ethics committee and taking signed informed consents from participants prior to study initiation".
So it is necessary to provide this information. In India over 3,000 years ago, turmeric, primarily use as a culinary spice and traditional Indian ayurvedic medicine, and its most important active ingredient is curcuminoids with effective doses is 500-2,000 mg of turmeric per day, often in the form of an extract with a curcumin concentration that is much higher than the amounts naturally occurring in foods, and the average Indian regular diet provides around 2,000-2,500 mg of turmeric

Conclusions
It is concluded that the easily-available, easily-suppliable, easily-applicable, side-effects-free, non-toxic, cost-effective, eco-friendly, and easily-preparable, high-diluted-potentialcommunity-biomedicine, Turmeric Extract (TE) or Turmeric MT (TMT), may act as preventive policy-developer-potential-21st-century-pandemic COVID 19 vaccine by achieving community-medicine-clinical-research-public-health-ecology-green-socio-economy-welfare-science-innovationstechnology communication-applications-advancements-issues. And within the new normal-future, it would be the foremost effective vaccine by using the ultra-high-diluted type of the community-biomedicines TE against day-to-day new virulent-coronavirus pandemics, oncology, and oral-health and multidisciplinary-care of COVID-19-survivors improving community-immunity or herd-immunity also, and students-NGO acts as 'Social-Vaccines' by their different human resource creating effective ecology-health activities that specialize in the notice of methods, research, science, and technology development for larger green-socio-economic-welfare, supported the theme "Vision 2040" that might help policymakers, solving virus-induced economic-condition globally.