Purpose: Compare long-term survival by sex after reperfusion therapies with simultaneous medical therapy of cardiovascular conditions.
Methods: AIS patients identified from the population-based register between 01Jan2011 and 31Dec2012 and classified into: 1) AIS + intravenous thrombolysis [group I], 2) AIS + mechanical thrombectomy with or without intravenous thrombolysis [group II], and 3) AIS + medical therapy alone (no reperfusion therapies) [group III]. Follow-up went through up until December 2016. Statistical approaches were employed for analyzing survival outcomes and their relationship with reperfusion therapy.
Results: 14,368 AIS patients (men 50.1%), 77.1±11.0 years-old. There was higher survival among those treated with intravenous thrombolysis (p <0.001); women treated with thrombectomy (p <0.001); and women <80 year-old without reperfusion therapy. The most common medications were antiplatelets (52.8%), associated with lower survival (p<0.001); and statins (46.5%), associated with higher survival. The regression model produced the following independent outcome variables associated to mortality: anticoagulant HR 1.53 (CI95% 1.44-1.63, p<0.001), diuretics HR 1.71 (CI95% 1.63-1.79, p<0.001), antiplatelet HR 1.49 (CI95% 1.42-1.56, p<0.001), statins HR 0.73 (CI95% 0.70-0.77, p<0.001), A-IIRA HR 0.93 (CI95% 0.89-0.98, p=0.008) and reperfusion therapy HR 0.88 (CI95% 0.81-0.97, p=0.009).
Conclusions: Under 80 year-old the women had a better outcome than men when treated with thrombolysis therapy and/or catheter-based thrombectomy and with medical therapy alone. The men had a better outcome when received intravenous thrombolysis. The chronic cardiovascular pharmacotherapy must be evaluated to determine their effects on the reperfusion therapy outcome and whether they should be included as factors in the decision to reperfusion.
Long-term survival after Acute Ischemic Stroke by types of reperfusion therapy, sex and chronic treatments of cardiovascular conditions.
Long-term Survival differences after reperfusion therapy.
Published on: Nov 29, 2018 Pages: 24-30
Full Text PDF
Full Text HTML
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat
Kyushu University, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
Global Journal of Cancer Therapy
University of Reims, France
Archives of Sports Medicine and Physiotherapy
Democritus University of Thrace , Greece
International Journal of Vascular Surgery and Medicine
Southeastern University, China
Trends in Computer Science and Information Technology
Peter J Catalano
Tufts University, USA
Archives of Otolaryngology and Rhinology
Rafal Tomasz Pawliczak
Medical University of Lodz, Poland
Open Journal of Asthma
Columbia University, USA
Journal of Novel Physiotherapy and Physical Rehabilitation
Domenico Antonio Restivo
Nuovo Garibaldi Hospital, Italy
Journal of Neurology, Neurological Science and Disorders
University of Nantes, France
Archives of Depression and Anxiety
Prof. Pierre Guertin
Laval University, Canada
International Journal of Pharmaceutical Sciences and Developmental Research
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."