Immune thrombocytopenia secondary to Cytomegalovirus infection during pregnancy: A case report and review of the literature

Gal Issakov*, Talya Finn, Aryeh Simmonds and Mordechai Ben David

Background: Cytomegalovirus (CMV) is a rare cause of Immune Thrombocytopenic Purpura (ITP) and even rarer during pregnancy. 

Case: A 27-year-old pregnant woman presented with severe thrombocytopenia in the latent phase of labor. She was treated with dexamethasone and platelet transfusions and underwent a successful vaginal delivery. The neonate had severe thrombocytopenia as well. Serology assays of the mother revealed CMV seroconversion with a negative Polymerase Chain Reaction (PCR). The neonate had a positive PCR and was treated with Intravenous Immunoglobulin (IVIG), steroids, platelets and Valganciclovir with a good response. The mother’s platelet count normalized three months later. 

Conclusions: CMV infection should be considered as a potential cause for severe thrombocytopenia during pregnancy and can lead to early detection and treatment for Congenital CMV.

Keywords:

Published on: Nov 11, 2022 Pages: 43-45

Full Text PDF Full Text HTML DOI: 10.17352/jgro.000115
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