Open Access Case Report Article ID: JGRO-8-215

    Immune thrombocytopenia secondary to Cytomegalovirus infection during pregnancy: A case report and review of the literature

    Gal Issakov*, Talya Finn, Aryeh Simmonds and Mordechai Ben David

    Background: Cytomegalovirus (CMV) is a rare cause of Immune Thrombocytopenic Purpura (ITP) and even rarer during pregnancy. 

    Case: A 27-year-old pregnant woman presented with severe thrombocytopenia in the latent phase of labor. She was treated with dexamethasone and platelet transfusions and underwent a successful vaginal delivery. The neonate had severe thrombocytopenia as well. Serology assays of the mother revealed CMV seroconversion with a negative Polymerase Chain Reaction (PCR). The neonate had a positive PCR and was treated with Intravenous Immunoglobulin (IVIG), steroids, platelets and Valganciclovir with a good response. The mother’s platelet count normalized three months later. 

    Conclusions: CMV infection should be considered as a potential cause for severe thrombocytopenia during pregnancy and can lead to early detection and treatment for Congenital CMV.


    Published on: Nov 11, 2022 Pages: 43-45

    Full Text PDF Full Text HTML DOI: 10.17352/jgro.000115
    CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat


    Global Views

    Case Reports

    Peertechz Tweets

    Pinterest on JGRO

    Google Reviews 11