Evaluation of Retinal Nerve Fiber Layer Thickness using Spectral Domain- Optical Coherence Tomography in Glaucomatous, Ocular Hypertensive and Normal Eyes and its Correlation with Visual Fields

Brijesh Patil, Anupama C Shetgar and Divya Teja V*

Objective: The aim of the study was to correlate the findings of peripapillary retinal nerve fiber layer (RNFL) thickness calculated with optical coherence tomography(OCT) with visual field changes in glaucomatous, ocular hypertensive and normal eyes.

Materials and Methods: 30 normal, 30 ocular hypertensive and 30 glaucomatous eyes were included in

the study. All underwent applanation tonometry, disc evaluation, octopus white on white (W/W) perimetry and OCT. Average and segmental RNFL thickness values were compared among all groups. A correlation

was sought between global indices of perimetry and RNFL thickness in ocular hypertensive group.

Results: Of the 90 eyes (mean age: 51.20±9.23 years), the mean RNFL thickness was significantly less in ocular hypertensives 83.83±26.20μm; P< 0.001) and glaucomatous eyes (55.33±34.72 μm; P <0.001), than in normal (103.27±16.23 μm). Ocular hypertensives had thinner RNFL in the superior, inferior, nasal and temporal quadrants (P < 0.001) when compared to normal. The RNFL thickness could not be significantly correlated with global indices of visual fields in ocular hypertensives.

Conclusion: Optical coherence tomography is capable of detecting changes at the level of RNFL in ocular hypertensive eyes with normal appearance of discs and W/W perimetry fi elds.

Keywords: Glaucoma; Ocular hypertension; Optical coherence tomography; Retinal nerve fiber layer; Perimetry

Published on: Mar 6, 2017 Pages: 10-13

Full Text PDF Full Text HTML DOI: 10.17352/2455-1414.000037
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