Open Journal of Bioinformatics and Biostatistics

    Abstract

    Open Access Research Article Article ID: OJBB-4-106

    Partial genomic analysis of spike-glycoprotein among Sudanese camels infected with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

    Ibrahim HS*, Kafi SK and Musa HA

    MERS-CoV was emerged for the first time in KSA; 2012 followed by a lot of new registered cases in the Middle East, European, American and African countries. The goal of this paper is to make a comparison between the partial spike-glycoprotein reference gene (NC_019843.3; genome region: 23864-24909 with 1046bp) with similar Sudanese camel sequences; using the NCBI data base. Creations of phylogenetic tree for those who were selected as reference genes from Middle East countries (Qatar, UKE, and KSA), south East Asia and African countries (Ethiopia, Egypt, Nigeria, Burkina Faso) with Sudanese sequences using ViPR website was done.

    This study revealed that most of the Sudanese sequences descending from each other’s with a lot of mutations area which mainly concentrated at positions; 155, 156, 158, 242, 840, 876 at nucleotide levels and to explain these more in-depth studies are recommended. 

    Keywords:

    Published on: Jul 31, 2020 Pages: 6-11

    Full Text PDF Full Text HTML DOI: 10.17352/ojbb.000006
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