Abstract

    Open Access Case Report Article ID: JCRO-8-190

    Fresh frozen plasma as a source of plasminogen for ligneous conjunctivitis: Case report and a review of the literature

    Benjamin J Park, David Camoriano, Mark C Vital, Patricia Chévez-Barrios, John D Goosey and Marcel Belloso*

    Purpose: To describe management of a patient with ligneous conjunctivitis secondary to plasminogen deficiency and review the literature on treatment with plasminogen.

    Design: Interventional case report.

    Methods: A 6-year-old Caucasian girl developed ligneous conjunctivitis recalcitrant to debridement and treatment with topical cyclosporin A and steroids. The literature was reviewed regarding treatment of ligneous conjunctivitis with plasminogen.

    Results: The patient was treated with plasminogen containing drops derived from her father’s fresh frozen plasma. The ligneous conjunctivitis resolved, and the patient was managed on these drops for the following 8 years, initiating treatment for flares and tapering according to clinical response.

    Conclusions: Plasminogen drops concentrated from fresh frozen plasma are a safe and effective option for long-term treatment of ligneous conjunctivitis.

    Keywords:

    Published on: Jul 19, 2021 Pages: 31-35

    Full Text PDF Full Text HTML DOI: 10.17352/2455-1414.000090
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