Can Strict Control of Renalase Present a New Treatment Alternative in Regulating Blood Pressure?

Suleyman Aydin* and Suna Aydin

Blood pressure is the pressure the blood in arteries applies on vessels. Abnormal blood pressure is a major public health problem commonly encountered in the population with normal blood pressure and intensive care patients. The two types of action that the heart performs are pumping blood and relaxing. The pressure exerted when the heart is pumping blood is the “systolic” blood pressure, and the pressure applied during the relaxation of the heart is the “diastolic” pressure. Although blood pressure is not always at the same level (with slight fl uctuations), normal blood pressure in adults is 120/80 mmHg. Lower blood pressure of 90/60 mmHg is hypotension, while higher blood pressure of 140/90 mmHg is hypertension [1]. Circulating high catecholamines (epinephrine and norepinephrine) can lead to a hypertensive crisis [2]. Renalase, a recently discovered fl avoprotein, degrade catecholamines [3, 4, 5]. Here it has been therefore claimed that blocking or enhancing the action of renalase migt help a strict control of regulating blood pressure.

Keywords:

Published on: Mar 14, 2017 Pages: 8-9

Full Text PDF Full Text HTML DOI: 10.17352/2455-2976.000037
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat