Etiological factors and comorbidities associated with the “Gender Dysphoria”: Definition, clinical contexts, differential diagnosis and clinical treatments

Giulio Perrotta*

Purpose: Starting from the concept of “gender dysphoria”, this research aims to find out if there is a correlation between GD and personality disorders.

Methods: Having selected the population sample of 255 subjects, having the requirements of age between 18 and 72 years and a declaration of perceived transsexuality, in transition or final, and domiciled in Italy for at least 5 years regardless of citizenship and nationality, it was decided to proceed with the clinical interview and administration of the PICI-1 (TA). It was considered unnecessary to administer the MMPI-II, as a previous study by the same author has demonstrated the effectiveness and efficiency of the test.

Results: Using the PICI-1, the following data emerged during the clinical interview: 1) The female population sample (FM) is smaller and more difficult to find; moreover, the perception of one’s transsexuality, as well as the desire to change one’s gender occurs in 100% (40/40) of cases before the age of 36. 2) The sample of the male population (MF) is more consistent and reports 84.13% (179/211) perceived or acted on the change before the age of 36. 3) The total population sample of 255 subjects had 97.5% (250/255) at least 5 dysfunctional personality traits among the disorders of PICI-1 cluster B (TA), i.e. borderline, histrionic, narcissistic, antisocial, sadistic and masochistic, while 56.55% (145/255) had at least 3 dysfunctional traits among the disorders of PICI-1 cluster A (TA), i.e. anxious, obsessive, depressed, phobic and somatic.

Conclusions: The research carried out gave further evidence that 97.5% (250/255) at least 5 dysfunctional personality traits among the disorders of PICI-1 cluster B (TA), i.e. borderline, histrionic, narcissistic, antisocial, sadistic and masochistic, while 56.55% (145/255) had at least 3 dysfunctional traits among the disorders of PICI-1 cluster A (TA), i.e. anxious, obsessive, depressed, phobic and somatic. However, in the future, studies are expected that subject children between the ages of 2 and 6 who already have the first dysphoric symptomatology to MRI and electroencephalogram every six months, following them up to adulthood, to understand if the anomalies represented are already present or not, and from that point begin to reason about the subject’s sexual evolution. Furthermore, a series of researches focused on a relevant and significant statistical sample is hoped, to be able to reconstruct the genesis of dysphoria and understand the exact incidence of serious psychopathological forms (including indirectly related disorders, such as paraphilias and different orientations sexual) and whether these are etiological factors, contributing factors or consequences of the primary condition, also and above all concerning the neurobiological and endocrinological clinical profiles.

Keywords:

Published on: Mar 6, 2021 Pages: 1-5

Full Text PDF Full Text HTML DOI: 10.17352/ijsrhc.000018
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