Familial Goiter and Related Disorders

E H Sidibe*, P J Guillausseau, A Warnet, J B Stanbury, J E Dumont

Synthesis, storage, secretion, delivery, and utilization of thyroid hormones are dependent upon specific enzymatic activity; inherited disorders may cause thyroid disease. Studies of a cretinous patient from consanguine marriage have indicated a limited response to thyrotrophic (TSH), both in synthesis of the specific thyroid protein thyroglobulin and in cell growth and division. Other similar response has been observed in a strain of mice. Familial goiter and hypothyroidism may occur when there is failure of the thyroid cell to transport iodide.

Keywords:

Published on: Nov 20, 2015 Pages: 48-48

Full Text PDF Full Text HTML DOI: 10.17352/ijcem.000010
CrossMark Publons Harvard Library HOLLIS Search IT Semantic Scholar Get Citation Base Search Scilit OAI-PMH ResearchGate Academic Microsoft GrowKudos Universite de Paris UW Libraries SJSU King Library SJSU King Library NUS Library McGill DET KGL BIBLiOTEK JCU Discovery Universidad De Lima WorldCat VU on WorldCat