Purpose: The aim of this study was to evaluate the safety and toxicity of intravenous use of White Tea Extract Liquid (WT) in rabbits through routine blood tests and biochemical and histopathological means.
Design and methods: This study used the WT product produced by the company and the New Zealand rabbits at 2.0~2.5 kg of weight. Rabbits were divided into two groups: Control and WT groups. In the WT group, the diluted WT injection volume needed to be injected was calculated according to their body weight on days 1, 4, 7 and 11...... for 4 weeks respectively. During the1, 2 and 4 weeks of the experiment, blood routine, blood biochemistry and the histopathological sections of the heart, spleen, lung, trachea, kidney, bladder, uterus, testicle, stomach, liver, small intestine, big intestine were evaluated in the study.
Findings: By comparison, the blood routine test did not deviate from the normal ranges provided by the diagnostic laboratory. The blood biochemical indexes of all experimental rabbits are within a reasonable range and did not detect clinically significant abnormalities between treatment and control groups. The WT had no obvious inflammatory change in the whole tissue and no harmful effect on the organs of various systems of the rabbits’ system for 4 weeks.
Conclusions: After intravenous injection for 4 weeks in rabbits, white tea herb atomization liquid did not produce obvious toxic effects on the animals.
Keywords:
Published on: Mar 16, 2023 Pages: 1-8
Full Text PDF
Full Text HTML
DOI: 10.17352/gjbbs.000018
CrossMark
Publons
Harvard Library HOLLIS
Search IT
Semantic Scholar
Get Citation
Base Search
Scilit
OAI-PMH
ResearchGate
Academic Microsoft
GrowKudos
Universite de Paris
UW Libraries
SJSU King Library
SJSU King Library
NUS Library
McGill
DET KGL BIBLiOTEK
JCU Discovery
Universidad De Lima
WorldCat
VU on WorldCat
PTZ: We're glad you're here. Please click "create a new query" if you are a new visitor to our website and need further information from us.
If you are already a member of our network and need to keep track of any developments regarding a question you have already submitted, click "take me to my Query."