Tuberculosis (TB) is a dangerous infection affecting about one third of the world population, despite the availability of affordable and effective chemotherapy, remaining one of the major causes of death from a single infectious agent worldwide. Here the measurement of ADA, LDH, protein and glucose has been advocated to help diagnose tuberculous pleural and peritoneal effusions in TB patients. Although considered definitive, microbiological tests have limited sensitivity and culture has to be prolonged for several weeks before being reported negative, in diagnosing tubercular pleural and peritoneal effusions and have more sensitivity and specificity as compared to pleural fluid culture and biopsy, and by estimation of values of these tests could be a useful tool for diagnosing tubercular pleural and peritoneal effusion. Thus a biochemical test is potentially useful, although high diagnostic accuracy is necessary.
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Published on: Oct 13, 2020 Pages: 72-77
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DOI: 10.17352/aprc.000060
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