Povidone Iodine (PVP-I) mouth gargle/nasal spray may be the simplest and cost effective therapeutic antidote for COVID-19 Frontier

Ibrahim Khalil and Parometa Barma*

Need an effective protocol for health workers against dangerous and unpredictable SARS CoV-2, a RNA lipid bi-layer enveloped beta-coronaviruses which contains Hemagglutinin Esterase (HE) protein binds with human gene through Angiotensin-Converting-Enzyme 2 (ACE2) and CD147 receptor. Povidone-iodine (PVP-I) has effective virucidal activity by those receptors inhibition and direct kill the virus by membrane disruption. PVP-I gargle, nasal spray and eye drop in case of accidental exposure is well tolerated easy use and has 2-3 hours contamination protection properties. So, uses gargle and nasal spray every 3 hours during shifting duty of health care provider which will cover the total protection and reduced social contamination. 

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Published on: Jul 21, 2020 Pages: 138-141

Full Text PDF Full Text HTML DOI: 10.17352/2455-5479.000093
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