Usefullness of Phytoestrogens in Treatment of Arterial Hypertension. Systematic Review and Meta-Analysis: Un Update

Garcia Garcia MA*, Rosero Arenas MA, Martinez Cornejo A and Perez Lluna L

Background: It has been suggested that phytoestrogens may have utility in the control of arterial hypertension.

Methods: We performed a systematic review and meta-analysis of randomized controlled trials, and the main outcome was the decrease of blood pressure.

Results: Decrease in systolic (- 0,15 mmHg, CI 95% from -0,24 to -0,05) and diastolic (-0,14 mmHg, CI 95% from -0,25 to -0,03) blood pressure were observed in patients taking phytoestrogens, but this difference was not clinically relevant. There can be a little greater decrease in Asian patients and in patients with higher baseline blood pressure values.

Conclusion: The global effect of phytoestrogens seems of small amount in reducing blood pressure. Nevertheless, it has not been realized a clinical trials about the efficacy of these products in no mild hypertensive patients, similar to real life.

Keywords: Phytoestrogens; Isoflavones; Soy protein; Blood pressure; Meta-analysis

Published on: Apr 12, 2016 Pages: 13-18

Full Text PDF Full Text HTML DOI: 10.17352/ach.000006
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